ABSTRACT
Background@#Pulmonary thromboembolism (PTE) is a significant contributing factor to vascular diseases.This study aimed to determine the prevalence of pulmonary thromboembolism and its predisposing factors in patients with COVID-19. @*Methods@#This cross-sectional study included 284 patients with COVID-19 who were admitted to Nemazee Teaching Hospital (Shiraz, Iran) between June and August 2021. All patients were diagnosed with COVID-19 by a physician based on clinical symptoms or positive polymerase chain reaction (PCR) test results. The collected data included demographic data and laboratory findings. Data were analyzed using the SPSS software. P ≤0.05 was considered statistically significant. @*Results@#There was a significant difference in the mean age between the PTE group and non-PTE group (P=0.037). Moreover, the PTE group had a significantly higher prevalence of hypertension (36.7% vs. 21.8%, P=0.019), myocardial infarction (4.5% vs. 0%, P=0.006), and stroke (23.9% vs. 4.9%, P =0.0001). Direct bilirubin (P =0.03) and albumin (P =0.04) levels significantly differed between the PTE and non-PTE groups. Notably, there was a significant difference in the partial thromboplastin time (P =0.04) between the PTE and non-PTE groups. A regression analysis indicated that age (OR, 1.02; 95% CI, 1.00‒1.004; P =0.005), blood pressure (OR, 2.07; 95% CI, 1.12‒3.85; P=0.02), heart attack (OR, 1.02; 95% CI, 1.28‒6.06; P =0.009), and albumin level (OR, 0.39; 95% CI, 0.16‒0.97; P =0.04) were all independent predictors of PTE development. @*Conclusion@#Regression analysis revealed that age, blood pressure, heart attack, and albumin levels were independent predictors of PTE.
ABSTRACT
Objective: To determine the indicators predicting the hospital mortality in pedestrian injured patients admitted to a level I trauma center in Southern Iran
Methods: This case control study was conducted in a Level-I trauma hospital in Shiraz. We selected all survived pedestrians who were admitted in the hospital with duration of admission more than 24 hours in one year from March 2016 to February 2017 as control group and compared with all non-survived pedestrian patients who expired in the hospital according to clinical from March 2012 to February 2017. Multiple logistic regression was performed to identify factors of hospital effect on pedestrian mortality and results expressed by Odds Ratios and their confidence intervals [CI] of 95%
Results: A total of 424 survived pedestrian injured patients were compare to 117 non-survived one. Their mean of survived and non-survived patients were 43.79]19.37 and 56.76]18.55 years respectively of which 361 [66.7%] and 180 [33.3%] were men and women, respectively. We found that the gender does not have any relation with hospital mortality [p=0.275]. Followed by, age is in relevance with mortality. Glasgow Coma Scale [GCS], Injury Severity Score [ISS], blood urea nitrogen [BUN], platelet [PLT], potassium [K] and hemoglobin [Hb] are significant factor which are associated with mortality. According to logistic analysis GCS 24 [p<0.001], thrombocytopenia <150,000 [p<0.001], and hypokalemia <3.5 [p=0.01] were independently associated with hospital mortality. Among them, GCS
Conclusion: The results suggest that GCS score, ISS, hemoglobin level, platelet count, BUN and potassium level might be independent factors associated with hospital mortality in pedestrian injured patients