ABSTRACT
We here report three cases of choroidal metastases with ocular pain and visual symptoms treated with palliative irradiation. Case 1: A 71-year-old woman was treated with chemotherapy for multiple metastases after surgery for right breast cancer. Sixteen years after surgery, a right choroidal metastasis with ocular pain and visual disturbance was detected. Palliative irradiation to this lesion achieved reduction in ocular pain and shrank the tumor. Case 2: A 54-year-old man presented with right ocular pain and abnormal vision and was diagnosed as having right lung cancer with multiple systemic metastases. Palliative irradiation to a right choroidal metastasis achieved reduction in ocular pain and shrank the tumor. Case 3: A 71-year-old woman developed left eye pain 17 months after surgery for lung cancer in the right upper lobe. She was diagnosed as having a left choroidal metastasis. After palliative irradiation, the tumor shrank and the left eye pain temporarily resolved. Palliative radiation therapy for choroidal metastasis with ocular pain and visual symptoms seems to be effective in improving symptoms.
ABSTRACT
<b>Objective</b>: Plasma cluster ions consist of positive and negative ions and are known to suppress the activity of total bacteria, mold fungi, viruses and allergens floating in the air. In terms of inactivating mite allergens, it was reported that plasma cluster ions suppressed the symptoms of atopic dermatitis in mice. In the present study we investigated the effect of plasma cluster ions on attenuating chronic allergic rhinitis and fatigue induced by mite allergens in humans.<br> <b>Design</b>: Sixteen subjects with specific immunoglobulin E (IgE) positive to <i>Dermatophagoides pteronyssinus</i>, who had symptoms of allergic rhinitis caused by house dust participated in a randomized double-blinded crossover trial. Subjects occupied a mite allergen challenge room and performed mental task for 4 hours with 25,000/cm<sup>3</sup> plasma cluster ions or without plasma cluster ions and rested for 2 hours outside of the room. We measured mite allergens (Der p1) on the floor using plastic dishes (90 mm diameter) placed at 5 points in the room. We also investigated the symptoms of allergic rhinitis using the Japanese Allergic Rhinitis Standard QOL Questionnaire (JRQLQ) during the 4-hour load and 2-hour rest and performance by Uchida-Kraepelin psychodiagnostic test during the 4-hour load.<br> <b>Result</b>: Plasma cluster ions inactivated 80–90% of Der p1 and attenuated the symptoms of nasal congestion in JRQLQ. Moreover, plasma cluster ions inhibited fatigue-induced impaired performance in Uchida-Kraepelin psychodiagnostic test compared to the case without the ions.<br> <b>Conclusion</b>: Plasma cluster ions reduce mite allergens and are effective for attenuating chronic allergic rhinitis and fatigue.<br>
ABSTRACT
In the present study, we investigated the effects of plasma cluster ions on moisturizing skin and increasing comfort sensation in healthy female volunteers. Thirty-two healthy women who often experienced dry skin participated in a randomized crossover trial. We evaluated skin moisture using the Corneometer CM825 and comfort sensation using the visual analogue scale. Plasma cluster ion concentrations of 25000 pcs/cm<sup>3</sup> increased skin moisture, while concentrations of 7000 pcs/cm<sup>3</sup> increased comfort sensation. These results suggest that plasma cluster ions have an effect on skin moisture contents and comfort sensation.<br>