ABSTRACT
BACKGROUND/AIMS: Dyslipidemia and obesity are risk factors for the development of acute myocardial infarction (AMI) that affect the clinical outcomes in patients. METHODS: We analyzed 2,751 consecutive AMI patients who underwent percutaneous coronary intervention (PCI) (mean age, 63.7 +/- 12.1 years). The patients were divided into four groups based on serum triglyceride levels and central obesity [Group Ia: triglycerides or = 200 mg/dL and (-) central obesity; Group IIb: triglyceride > or = 200 mg/dL and (+) central obesity]. In-hospital outcome was defined as in-hospital mortality and complications. One-year clinical outcome was compared and defined as the composite of 1-year major adverse cardiac events (MACE), including death, recurrent MI, and target vessel revascularization. RESULTS: Total MACE developed in 502 patients (18.2%), while 303 patients (11.0%) died prior to the 1-year follow-up visit. In-hospital complications and in-hospital mortality were not different among the four groups. One-year clinical outcomes based on triglyceride levels (Group I vs. Group II) were not different. In addition, there were no differences in clinical outcomes in patients with a triglyceride level < 200 mg/dL, regardless of central obesity. One-year MACE rates were not significantly different among the four groups. CONCLUSIONS: There was no significant difference in the 1-year MACE rate based on the triglyceride level and presence of central obesity in patients with AMI who underwent PCI.
Subject(s)
Humans , Dyslipidemias , Follow-Up Studies , Hospital Mortality , Mortality , Myocardial Infarction , Obesity , Obesity, Abdominal , Percutaneous Coronary Intervention , Risk Factors , TriglyceridesABSTRACT
BACKGROUND/AIMS: Dyslipidemia and obesity are risk factors for the development of acute myocardial infarction (AMI) that affect the clinical outcomes in patients. METHODS: We analyzed 2,751 consecutive AMI patients who underwent percutaneous coronary intervention (PCI) (mean age, 63.7 +/- 12.1 years). The patients were divided into four groups based on serum triglyceride levels and central obesity [Group Ia: triglycerides or = 200 mg/dL and (-) central obesity; Group IIb: triglyceride > or = 200 mg/dL and (+) central obesity]. In-hospital outcome was defined as in-hospital mortality and complications. One-year clinical outcome was compared and defined as the composite of 1-year major adverse cardiac events (MACE), including death, recurrent MI, and target vessel revascularization. RESULTS: Total MACE developed in 502 patients (18.2%), while 303 patients (11.0%) died prior to the 1-year follow-up visit. In-hospital complications and in-hospital mortality were not different among the four groups. One-year clinical outcomes based on triglyceride levels (Group I vs. Group II) were not different. In addition, there were no differences in clinical outcomes in patients with a triglyceride level < 200 mg/dL, regardless of central obesity. One-year MACE rates were not significantly different among the four groups. CONCLUSIONS: There was no significant difference in the 1-year MACE rate based on the triglyceride level and presence of central obesity in patients with AMI who underwent PCI.
Subject(s)
Humans , Dyslipidemias , Follow-Up Studies , Hospital Mortality , Mortality , Myocardial Infarction , Obesity , Obesity, Abdominal , Percutaneous Coronary Intervention , Risk Factors , TriglyceridesABSTRACT
A reliable method of measuring r-CBF should give further insight into the pathophysiology of ischemic symptom and might facilitate decisions regarding patient management. In order to study the correlation between r-CBF value and ischemic cerebrovascular disease, 80 patients who were admitted to the Department of Neurosurgery, Kyung Hee University Hospital, between January 1983 and December 1986 were evaluated by 133-Xenon inhalation method. The results were as follows: 1) There was significant decrease of CBF in patients with ischemic cerebrovascular disease than CBF of control group. 2) There was significant decrease of CBF in patients of completed stroke than TIA or RIND patient. 3) 67.5% of patients showed more decreased hemispheric value on the symptomatic side than that of opposite side. 4) r-CBF was decreased significantly in the region corresponding to each vascular territory infarction. 5) There was significantly lower CBF in patient with hematocrit in range 47 or more than in patient with hematocrit in the range 36-46. 6) Group of patients with progressing neurological manifestation showed significantly decreased CBF than that of group of patients improved. It is suggested that r-CBF measurement may be helpful for evaluation and management of the patient with ischemic cerebrovascular disease.
Subject(s)
Humans , Hematocrit , Infarction , Inhalation , Neurologic Manifestations , Neurosurgery , StrokeABSTRACT
We have experienced 80 cases of primary pontine hemorrhage who were admitted to Kyung Hee Medical Center from October 1982 to September 1987. All cases were confirmed by brain CT scan and treated conservatively. The hematomas have classified according to their modes of extension on computerized tomography. The outcome was assessed on their basis of activity of daily living. The results were as follows: 1) Pontine hemorrhage represented 7.8% of all primary intracerebral hemorrhages. 2) Age distribution was ranged from 3rd decade to 7th decade, and 65% of them were in 4th and 5th decade. The ratio of male to female was 5:3. 3) 91.2% of patients had history of systemic hypertension and most of them did not received antihypertensive medication. 85% of patients showed the systolic blood pressure on admission above 160mmHg. 4) Outcome I and II according to ADL were only .5%. The prognosis was affected by level of consciousness, blood pressure on admission, and size and extent of hemorrhage. 5) Majority of causes of death were injury to brain itself, and the mortality rate was 33.7%.
Subject(s)
Female , Humans , Male , Activities of Daily Living , Age Distribution , Blood Pressure , Brain , Cause of Death , Cerebral Hemorrhage , Consciousness , Hematoma , Hemorrhage , Hypertension , Mortality , Prognosis , Tomography, X-Ray ComputedABSTRACT
We have experienced 80 cases of primary pontine hemorrhage who were admitted to Kyung Hee Medical Center from October 1982 to September 1987. All cases were confirmed by brain CT scan and treated conservatively. The hematomas have classified according to their modes of extension on computerized tomography. The outcome was assessed on their basis of activity of daily living. The results were as follows: 1) Pontine hemorrhage represented 7.8% of all primary intracerebral hemorrhages. 2) Age distribution was ranged from 3rd decade to 7th decade, and 65% of them were in 4th and 5th decade. The ratio of male to female was 5:3. 3) 91.2% of patients had history of systemic hypertension and most of them did not received antihypertensive medication. 85% of patients showed the systolic blood pressure on admission above 160mmHg. 4) Outcome I and II according to ADL were only .5%. The prognosis was affected by level of consciousness, blood pressure on admission, and size and extent of hemorrhage. 5) Majority of causes of death were injury to brain itself, and the mortality rate was 33.7%.