ABSTRACT
Dermatofibrosarcoma protuberans (DFSP) is a relatively uncommon soft tissue neoplasm of cutaneous fibrous tissue with low to intermediate grade malignancy. Most of this tumour is focal origin; however the sequential occurrence of the two masses over breast and inguinal region in our case probably represents multifocal origin rather than metastases. To the best of our knowledge case of DFSP having multifocal origin as was our case, have rarely been documented in the literature.
ABSTRACT
Background: Most of the patients suffering from malaria shows reduced Red cell count, leukopenia and varying degree of thrombocytopenia but it is rarely associated with haemorrhagic manifestations. Aims & Objective: This study was undertaken to correlate the incidence and severity of thrombocytopenia with the prevalent species of malaria. Material and Methods: Total 1480 Patients were included in this study after positive identification on PSMP. Platelet count was done by haematology analyser (Sysmax Kx 21). Results: Incidence of thrombocytopenia was seen in 83.80% and 74% cases of P. falciparum and P. vivax malaria respectively. Severe thrombocytopenia in P. falciparum was found in 7.70% cases while in P. vivax 3.67% cases. No difference was observed in incidence of thrombocytopenia in both age groups in relation to both prevalent species. In paediatric age group, significant leukopenia was found in 22.22% Cases of P. falciparum in comparison to P. vivax (14.96%). Hb less than 10 mg/dl was found in 66.11% cases in P. Falciparum while in P. vivax it was found in 40.13% cases. In adults leukopenia was found in 27.46% Cases of P. falciparum in comparison to P. vivax 22.61% cases. Hb less than 10 mg/dl was found in 41.28% cases in P. falciparum while in P. vivax it was found in 28.57% cases. Conclusion: Severe thrombocytopenia is commonly associated with P. falciparum malaria however severe thrombocytopenia also observed in P. Vivax malaria. In both species of malaria significant number paediatric patients present with low Hb level compared to adults. In P. vivax malaria significant number of adult patients presented with leukopenia as compared to paediatric patients.
ABSTRACT
Background: Malaria is a major health problem and infects many individuals despite of various efforts to control it. The present study was aimed to observe characteristics of malaria, seasonal variation and prevalence of malaria in our region. Methods: This retrospective study was conducted in our institute from period of January 2012 to December 2012. All the fever cases undergone investigations for malarial parasites were included in present study for defined time period. All the laboratory data of the patients having fever were retrieved from the Pathology Laboratory of our institute. Results: out of total 32674 reports studied 4907(15.01%) were positive for malaria with overall Slide positivity rate and slide falciparum rate were 15.01% and 38.29% respectively. Incidence of malaria occurs throughout year with increased incidence of P. falciparum in monsoon. Conclusion: In the present study incidence of malaria was higher in monsoon in comparison to other seasons. But throughout the year no declining trends in incidence of malaria was observed. P. vivax malaria was more commonly observed in our study but incidence of P. falciparum increased in monsoon.