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Objective To explore the diagnostic value of ultrasound in thyroid nodular disease.Methods Eighty-seven patients with thyroid nodule in hospital from 2010-2011 were taken ultrasound examination,including 23 cases with benign nodules and 64 cases with malignant nodules.Univariate analysis and mutivariate Logistic regression analysis were taken to test the ultrasonic index (internal echo,boundary,size,shape,microcalcifications,and aspect ratio) for discovery of the best diagnostic ultrasonic index to identify benign and malignant nodules.Results The ultrasound in the patients with malignant thyroid nodules showed the hypoecho,unclear border,irregular shape,microcalcifications,low blood supply,the aspect ratio ＞ 1.The ultrasound in the patients with benign thyroid nodules showed high or equal echo,clear border,regular shape,high blood supply,and the aspect ratio≤ 1.The ultrasonic indices between two groups had statistically significant difference (P ＜ 0.05).The shape and microcalcifications were the best ultrasonic diagnostic index to indentify the benign and malignant nodules with an EXP(B) 20.12 and 19.14,respectively.Conclusions The ultrasound is helpful in the diagnosis of thyroid nodular disease and identification of benign and malignant thyroid nodules.The ultrasonic images are the basic data for the clinical diagnosis of thyroid nodules.
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Objective To evaluate the therapeutic effect of spironolactone on schistosomal pulmonary arterial hypertension(SPAH). Methods A total of 62 patients suffered from hepatosplenic schistosomiasis with pulmonary arterial hypertension were divided into the spironolactone group(n=31) and control group (n=31). All the patients underwent serial echocardiography and the clinical effect before and after the treatment was evaluated by assessing the mean pulmonary arterial pressure (mPAP) and pulmonary arterial diameter (PAD). At the same time, the varieties of the clinical symptoms, signs and the distance of the 6-minute walking test (6-MWT) were investigated. Results In spironolactone group, mPAP(-x±s) decreased from (31.8±7.1) mmHg to (21.2±2.1) mmHg, PAD(-x±s) decreased from (28.0±5.0) mm to (20.0±3.5) mm before and after the treatment respectively(P<0.01). There were significant differences in mPAP, PAD, the distance of 6-MWT and the heart function before and after the treatment in the spironolactone group. However, the data did not show the significant difference in the control group. Conclusion The therapeutic effect of spironolactone in the treatment of SPAH is satisfactory.
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Objective To explore the relationship between the liver fibrosis scales of B-ultrasound and the serological indicators of schistosomiasis liver fibrosis for guiding clinical diagnosis and treatment. Methods A total of 206 schistosomiasis patients including the acute, chronic and advanced were classified by ultrasonic evidences, and serological indicators of liver fibrosis were detected. The correlation among them was analyzed statistically. Results Ultrasonic diagnosis was 0 scale for acute group and control group, and Ⅱscale for chronic group, as well as Ⅲ scale for advanced group. Advanced group had the highest level of 4 serum indicators of liver fibrosis, and chronic group ranked the middle level, and acute group had the lowest level. The more advanced the ultrasonic scales of liver fibrosis, the higher level the 4 serum indicators. Conclusions There is a consistency relationship between ultrasonic classifications of liver fibrosis and serological indicators in schistosomiasis patients. It also conforms to clinical diagnosis. When ultrasound is applied in schistosomiasis, serological detection is essential and it could make up for the shortage of ultrasonic findings and give better guidance for clinical diagnosis and treatment.
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Objective To explore the classification of ultrasound images of hepatic parenchyma of schistosomiasis japonica. Methods A total of 2 918 hepatic photographs were selected and classified . All the photographs came from the former research project, which had B ultrasonography examination for residents from three medium endemic villages adjacent to the Dongting Lake,such as Huarong, Hanshou, Lixian, and for advanced schistosomiasis patients in Xiangyue hospital. Results For these hepatic parenchyma images there were five types, including normal echogenic dots (91 photographs), widened echogenic dots (1 757 photographs), echogenic paths(121 photographs), e-chogenic strips (467 photographs) and echogenic bands (482 photographs), etc. , and eight patterns, including nomal echogenic dots (91 photographs), widened echogenic dots (1 757 photographs), echogenic slices (59 photographs), echogenic patches (62 photographs), fine strips (323 photographs), coarse strips (144 photographs), narrow reticular(280 photographs) and wide reticular (202 photographs). Conclusion B ultrasonic images of the liver of schistosomiasis japonica can be classified into five types and eight patterns.