ABSTRACT
Objective To further study the clinical efficacy and safety of salvianolate injection for the treatment of angina pectoris in coronary heart disease (CHD)with heart-blood stagnation syndrome. Methods A randomized imitative-blind mutli-center clinical trials with positive control and 3 parallel tests was carried out in 480 cases. The patients were divided into three groups: the control group received salviane injection 20 mL (n=120), the treatment group 1 (n=240) and treatment group 2 (n=120) received salvianolate injection in a dosage of 200 mg and 400mg respectively . After 14-daytreatment , the clinical efficacy and safety of salvianolate were observed. Results The total angina pectoris efficacy rates were 88.085 %in treatment group 1, 89.744 %in treatment group 2 and 67.257 %in control group (P
ABSTRACT
Objective To evaluate the safety and efficacy of Safflower Yellow Injection(SYI)in treating coronary heart disease and angina pectoris(CHD-AP)with heart blood stagnation syndrome(HBSS).Methods A randomized,positive parallel contral and multi-center clinical trial was adopted.The SYI injection group was treated with SYI and Xiangdan injection group with Xiangdan injection by intravenous dripping for 2 weeks.Results The efficacy on angina pectoris,electrocardiogram,and traditional Chinese medicine(TCM)syndrome in SYI injection group was superior to that in Xiangdan injection group,showing significant differences(P