ABSTRACT
Some common complications of aging such as nutritional deficiency, lack of physical activity, the increase in body fat percentage and the prevalence of specific diseases may indirectly affect the immune system function. Thus, this study aimed to determine the effect of a 6-month moderate aerobic training program on interleukin-2 [IL-2] receptor [CD25 cells], IL-2 and salivary immunoglobulin A [sIgA] levels in elderly men. Forty sedentary and healthy aged men [mean age, 65 +/- 2 years] were randomly divided into experimental [n=20] and control [n=20] groups. The experimental group performed moderate aerobic training three times a week for 6 months, while the control group did not perform any regular training. Then CD25 cells, the level of IL-2, sIgA and VO2max were determined for each participant. The results showed that aerobic training significantly increased VO2max, CD25 cells, the level of IL-2 and sIgA in the experimental group. It seems that the moderate aerobic training for 6 months can be very effective to delay the process of immune system aging
ABSTRACT
Osteoarthritis [OA] is characterized by progressive erosion of articular cartilage and the bone growth on joint's margins. It is an important cause of long term health problems and the most frequently reported reason for long lasting disability. To evaluate the pain and the disability in patients with OA and also comparing of these parameters in different joints of upper and lower extremities. In the present cross-sectional study, 200 patients with OA were diagnosed by a rheumatologist using standard criteria. The severity of disability was evaluated using the clinical Health Assessment Questionnaire [HAQ]. Disability index was statistically different in diverse joint groups and OA of upper and lower limbs both with lower indices. However, no difference in occurrence of disability was found when the sexuality, educational and marital statuses were compared. There was consistently significant difference between age average and the presence of disability in different groups of joints. The age and the disability index showed a statically significant positive correlation [Pearson r = 0.17, P= 0.01]. Multiple variables [ANOVA] test also was indicative of a significant difference in disability of different joint groups when the age was regarded as a predisposing cofactor. Multiple joints involvement is considered as a risk factor for disability in OA patients which increases by ageing