ABSTRACT
Objective: the objective of this study was to compare pregnancy outcome of women aged 40 and above with those of 20- 30 year
Study design: cross-sectional and comparative study
Setting: department of obstetricsand Gynecology Peoples University of Medical and Health Sciences Nawabshah
Duration: from 1st July 2011 to 31st Dec 2011
Material and method: consecutive 100 cases of women aged 40 and above and 100 cases of women aged between 20-30 years were included in the study, and labeled as group A and B respectively. All patients were under gone general and physical examination and routine laboratories tests. The biological effects of age on the pregnancy outcome were observed, and results were tabulated
Result: the mean age for case group was 41.56 +/- 2.06 and that for control group 25 +/- 2 years. Among the maternal complication of increased maternal age were abortion in early half and preterm labor in second half of pregnancy [10%] and [12%] respectively. Hypertension [14%] and Diabetes [9%] were more common than in younger age group. Risk of fetal malformation [11%] was also three fold more than younger group [2%]. Increased rate of c- section [6%] was seen more with advanced maternal age with high parity
Conclusion: the advanced maternal age is candidate with high risk of maternal and perinatal morbidity andmortality. Appropriate management can be formulated to ensure better maternal and fetal outcome during pregnancy