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1.
Article | IMSEAR | ID: sea-202499

ABSTRACT

Introduction: Cardiac dysfunction in patients with cirrhosisoccurs in the setting of a circulatory dysfunction characterizedby a marked splanchnic arterial vasodilation. Circulatory changescan lead to the cardiac dilatation of the left chambers and thedevelopment of functional changes in the heart. The present studyis intended to assess cardiac functions in patients of liver cirrhosis.Material and methods: It was a cross sectional study conductedamong 74 diagnosed cases of liver cirrhosis, admitted todepartment of general medicine, KIMS Hospital during the 6months study duration.Results: Overall LVDD was diagnosed in 59 cases (79.73%).Out of which, 47.29% cases presented with Stage 1 (impairedrelaxation) LVDD, Stage 2 LVDD (pseudo normal) among31.08% and only one patient had severe restrictive type of(Stage 3) LVDD.Conclusion: Left ventricular diastolic dysfunction iscommonly associated with advancement of hepaticdysfunction while systolic function is maintained till advancedhepatic failure

2.
Article | IMSEAR | ID: sea-202193

ABSTRACT

Introduction: Dengue is the most common arboviral diseaseworldwide and is usually endemic, but several epidemics havebeen recorded. Dengue fever is associated with electrolytedisturbances.Material and methods: This study was a cross sectional,descriptive and non interventional study conducted onpatients of Dengue fever, during the period of 18 monthsbetween October 2016 to March 2018 in a tertiary care centre.This study was conducted to find relation between electrolytedisturbances in patients with dengue fever.Results: The majority of the patients 136 (67.32%) weremales while 66 (32.67%) were female patients. The majorityof patients 84.65% were with Dengue fever and 14.35%patients were with Dengue hemorrhagic fever and 0.99%patients were with Dengue shock syndrome. Hyponatremiaand hypokalemia was the frequent electrolyte disturbancesfound in dengue patients. The mean value of serum sodiumwas 133.92mEq/L and of serum potassium was 3.62mEq/L.There exists a positive and significant correlation betweendifference in serum sodium (r = 0.38) and potassium levels(r = 0.41) with Dengue clinical syndrome (DF, DHF, andDSS) which implies that as the difference between the levelsincreases, greater are chances of the Dengue fever towardsDHF or DSS.Conclusions: Hyponatremia was the most frequent electrolytedisturbance and hyperkalemia was least common observed inpatients with Dengue viral infection. Mild hyponatremia andmild hypokalemia were more common among patients ofDengue fever whereas moderate and severe hyponatremia andhypokalemia were more common among Dengue hemorrhagicfever (DHF) and Dengue shock syndrome (DSS).

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