ABSTRACT
Introduction: Myocardial infarction (MI) is one of the leading causes of mortality in India. The associated risk factors vary with respect to geographical and cultural difference in patients of MI. Objective: To study the association between known risk factors and MI in patients visiting tertiary rural health care center. The study design was Unmatched Case Control type. Patients of age 18 or above diagnosedMethod: of AMI were included as cases. Patients of age 18 or above without prior history of heart disease were included as controls. Pregnant women and patients with coexisting cardiogenic shock, any significant chronic medical illness was excluded. The history of hypertension, Diabetes, family history of CHD, stress in past 1 year, history of alcohol intake, History of tobacco addiction, type of activity at work were recorded. The comparison of case and controls were done using Chi square test, Fisher's Exact Test and Odds ratio, wherever applicable. A one sided “p” value of <0.05 was considered significant. Of the 230 studyn Results: participants included in the study, 100(43.5 %) were cases and 130 (56.5%) were Control, respectively. Except for history of stress, there was no statistical difference between number of cases and controls. Conclusion: The known risk factors of MI were not found associated with the disease. There is a need for conduct of study with larger sample size for confirmation of the study results.
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Background: Patient reported treatment outcomes is a better way to measure the quality of life (QOL). This study was undertaken to translate the speech handicap index (SHI) and voice handicap index (VHI) in Marathi language and its linguistic validation and cross-cultural adaptation in patients of head and neck squamous cell cancer (HNSCC). Methods: SHI and VHI were translated into Marathi with prior permission from the respective authors of original English questionnaire (RAs). The translation procedure for each tool included two forward translations (English to Marathi), the formation of first intermediate Marathi translation (FIT), two back translations (Marathi to English) of FIT, and interim Marathi translation (IT) formation. The second intermediate Marathi translation (SIT) was prepared after face validation of IT by a subject expert. Pretesting of SIT was done in 20 patients of HNSCC to validate linguistic and cross-cultural adaptation. By incorporating the patient’s suggestions, the final Marathi translation was prepared and sent to primary authors for approval. Results: The grammatically and conceptually acceptable and face validated SIT was prepared and administered to HNSCC patients. The patients of the oral cavity and larynx were in SHI and VHI group, respectively (ten patients in each group). The questionnaire was well understood reflecting its linguistic and cross-cultural adaptation. Some of the patients suggested changes in a few words which were then corrected, rechecked with back translation, and final Marathi translated questionnaire was prepared. It was approved by RAs. Conclusion: Marathi translation of SHI and VHI are well accepted and comprehensible. It can be used for future studies.
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Introduction: The aim of the present study was to compare two immobilization systems for comparison of setup errors in targeted radiotherapy. Methods: Retrospective analysis was done for the patients undergoing radiotherapy from May 2012 to December 2018 at our institution. Immobilization was performed on 30 patients sessions (Vacuum cushion i.e., Vac-Lok™ = 15; Thermoplastic mould i.e., Pelvicast pelvic masks = 15). A total of 763 cone-beams were analysed. The target lesion location was verified by cone-beam computed tomography (CBCT) prior to each session, with displacements assessed by CBCT simulation prior to each treatment session. Systematic setup errors, random setup errors, isocenter deviations in the Medio-lateral (ML), Supero-inferior (SI), Antero-posterior (AP), Rotation (yaw) directions of the patient position was calculated. Results: On comparing the Vac-Lok™ and Pelvicast pelvic masks group with respect to Systematic and random error in the lateral, longitudinal, vertical and YAW direction, no statistically significant difference was seen except the random error in YAW direction (P=0.037, Unpaired t-test). There was no difference observed in comparing the isocentric deviation. Conclusion: It was inferred and concluded that using a vacuum cushion for pelvic radiotherapy provides no added benefit compared to using a thermoplastic mould. Thermoplastic mould is recommended for patients receiving pelvic radiotherapy to improve overall reproducibility
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Background: Hypertension causes morbidity as well as increases mortality either by acting independently or by affecting multiple organ system. Risk factors of hypertension are categorized as modifiable or non-modifiable risk factors. Early identification of these risk factors is not only essential for prediction of hypertension and but also to reduce effect associated with it.Methods: The present descriptive cross-sectional study was carried out at field practice area of tertiary care teaching hospital of western Maharashtra. Total 1537 sample sized was achieved using systematic random sampling technique. All the village individuals, both male and female, over 18 years of age were included in the study whereas, pregnant women, extremely debilitated persons and subjects who were not willing to give informed consent were excluded. A pre-designed and pre-tested questionnaire was used for data collection.Results: In present study the prevalence of hypertension and pre-hypertension was 11.49% (117). On regression analysis risk factors like age, BMI, high salt intake, family history of blood pressure etc., were found to be associated with hypertension.Conclusions: The present study showed a higher prevalence of both hypertension among the rural population and risk factors such as age, obesity, elite social class, high salt intake, family history of blood pressure were the predictors of the hypertension.
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Background: The consumption of high sugar contained carbonated drinks is more prevalent among youngsters. The excess consumption of carbonated drink has been associated with many adverse health effects. Aims & Objective: (1) To study Knowledge, Attitude and Practices (KAP) regarding consumption of carbonated drinks among medical students. (2) To suggest suitable recommendation for the health promotion. Material and Methods: A cross sectional descriptive study was conducted to assess the knowledge, attitude and practice of students regarding carbonated drinks. The study participants were second year medical student of Medical College situated in a rural area of western Maharashtra. Self-structured pretested questionnaires were given to the 110 students for study purpose. Results: Out of all students 52 (48%) were reported that they had started to drink carbonated drink at the age less than 10 years. Majority of students consider obesity (28.2%) as side effect associated with consumption of carbonated drink followed by bone decay (11%) and dental caries (9%). Conclusion: The health education and primordial prevention would be the best way to adopt healthy life style and combat the problems associated with the consumption of carbonated drinks.