ABSTRACT
Background: this study was done to determine the types and outcome of various arrhythmias in Acute Myocardial Infarction within first 24 hours: It was a descriptive study. The study was conducted at Department of Medicine and Coronary care, Bahawal Victoria Hospital, Bahawalpur, from June 2007 to June 2008
Patients and Methods: one hundred cases, both male and female suffering from Acute Myocardial Infarction admitted within first 24 hours were selected for study. The inclusion criteria were age of 20 years and above myocardial infarction, confirmed by ECG and cardiac enzymes. History, clinical examination, and various investigations. were documented The type of arrhythmias, type of Myocardial infarction in relation to age, sex and their outcome was observed and recorded
Results: the age range of patients included in this study was between 20 to 80 years [mean 50 +/- 29.8 years]. The patients included 74 [74%] males and 26 [26%] females. Out of these, 64% patients developed arrhythmias during first 24 to 48 hours. Tachyarrhythmia's occurred in 42 [65%] cases and included supraventricular tachycardia in 12 [18.7%], premature contractions in 11 [18.7%], ventricular tachycardia in 10 [15.7%] and Junctional Tachycardia ii"] 3[4, 6%]. Brady arrhythmias were observed in 22 [35%] patients with complete heart block in 4[18%] cases, 1st and 2nd degree heart blocks in 6[27%], bundle branch blocks in 9 [4.06%] arid one [1 .5%] Sino-atrial. Block. Majority patients [80%] with anterolateral infarction, 75% with lateral. Wall infarction and 72% with inferior wall involvement developed arrhythmias of these cases of acute myocardial infarction that developed arrhythmias 16 [23.5% died
Conclusion: the study concludes that AMI involves dominantly males and 64% of patients developed arrhythmias with 1st 24 hours. Tachyarrhythmia were more common [65%] ·and mortality rate was 23.5% during first twenty four hours of AMI due to arrhythmias
ABSTRACT
Objective: This study was designed to investigate the serum insulin levels among hypertensive patients and to study the possible relation with blood pressure, BMI, cholesterol and triglycerides. Study Design: Comparative study
Methods: Twenty non - obese, non diabetic patients with essential hypertension and twenty normotensive controls were studied at the PMRC, Research Centre, F.J. Medical College, Lahore. Blood was drawn for serum insulin levels, Blood sugar, cholesterol and triglycerides after an overnight fast. Blood pressure and body mass index [BMI] were recorded and results analyzed by using SPSS Package
Results: Showed significantly high [P<0.001] levels of insulin [13.02 +/- 1.95 mu/l] among the Hypertensives compared to controls [10.91 +/- 1.45mu/l]. A significant positive correlation was found [r = 0.439 and Sig. 0.05] between serum Insulin and Serum cholestrole. Correlation of serum Insulin with Diastolic blood pressure, triglycerides, BMI and blood sugar level was weakly negative and insignificant
Conclusion: It is concluded that serum insulin levels are significantly higher among Hypertensives and significantly correlated with serum cholesterol levels compared to controls