ABSTRACT
Testicular germ cell tumors (GCT) are a diverse group of neoplasms, broadly divided into seminomatous and non seminomatous types, with varying histomorphology. Mixed germ cell tumors express more than one germ cell component. Somatic type malignancy occurring in testicular GCT is rare. Most often these components present as metastasis, particularly following chemotherapy, rather than primarily involving the testis. We describe a rare case of a young adult with no significant past history, who presented with testicular mass which on histology revealed a non-seminomatous mixed germ cell tumor with additional somatic type malignancy component of a rhabdomyosarcoma.
ABSTRACT
We report a 5-year-old girl with congenital hepatic fibrosis who presented with clubbing and cyanosis. Partial pressure of oxygen was 40 mmHg with oxy-gen saturation of 70% on room air, which improved to 128 mmHg and 92% on inhalation of 100% oxygen. Macroaggregated albumin scan showed 58% shunting to the brain, suggestive of severe hepatopulmonary syndrome. Echocardiogram and pulmonary angiogram ruled out pulmonary hypertension. Four weeks after living-related liver transplantation, she had normal blood gases and reduction in shunting to 7% on macroaggregated albumin scan.
Subject(s)
Child, Preschool , Female , Follow-Up Studies , Hepatopulmonary Syndrome/complications , Humans , Liver Cirrhosis/congenital , Liver Transplantation , Living Donors , Technetium Tc 99m Aggregated Albumin/diagnosis , Treatment OutcomeABSTRACT
A clinicopathological analysis of 18 cases of primary intracranial malignant lymphoma encountered in the period 1980 to 1994 is presented. The total SOL's in this period was 924, the incidence of malignant lymphoma working out to 2%. The patients age ranged from 14 to 72 years with maximum prevalence in the sixth and seventh decade. The male to female ratio was 2:1 and the patients presented with evidence of CNS deficit, change in mental status or raised ICI. 15 cases had a single site of involvement while 3 patients had multicentric lesions. As far as could be determined none of the cases had evidence of immunesuppression and test for HIV carried out in five cases was negative. All the tumors were subjected to light microscopy and the diagnosis was confirmed either by ultrastructural examination or immunohistochemistry. 13 tumors were large cell high grade lymphomas while the rest revealed smaller cells. Eleven patients received post operative radiotherapy and two were given post operative chemotherapy. The outcome of the patients was poor in most cases, fifteen out of eighteen died within two years.
Subject(s)
Adolescent , Adult , Aged , Central Nervous System Neoplasms/pathology , Female , Humans , Lymphoma, Non-Hodgkin/pathology , Male , Middle AgedABSTRACT
Ten cases of cystosarcoma phyllodes are reported along with review of literature. The pathological features are outlined and principles of management are discussed.
Subject(s)
Adolescent , Adult , Breast Neoplasms/pathology , Female , Humans , Middle Aged , Phyllodes Tumor/pathology , PrognosisABSTRACT
The term ossifying lipoma is used to describe a rare case of lipoma when its mature adipose tissue shows foci of chondrification and ossification. We are presenting here, a case report of a large sized ossifying lipoma in the anteromedial compartment of the left thigh of a 55 year old farmer.