ABSTRACT
Nocardia is a significant opportunistic pathogen in patients with compromised immunity. Nocardia asteroides was isolated from subcutaneous abscesses on the left thigh and shoulder of a renal transplant recipient. Direct examination of the aspirated pus showed branching filaments that were gram-positive and acid fast. The abscesses were drained and the patient responded to high dose co-trimoxazole therapy.
Subject(s)
Abscess/drug therapy , Abscess/etiology , Abscess/therapy , Adult , Drainage/methods , Humans , India , Male , Kidney Transplantation , Nocardia asteroides/pathogenicity , Shoulder , Subcutaneous Tissue , Thigh , Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic useSubject(s)
Adolescent , Adult , Aged , Anti-Bacterial Agents/pharmacology , Child , Child, Preschool , Drug Resistance, Bacterial , Erythromycin/pharmacology , Female , Hemolysin Proteins/biosynthesis , Humans , Incidence , India/epidemiology , Infant , Male , Middle Aged , Streptococcal Infections/epidemiology , Streptococcus/classification , Streptococcus agalactiae/classification , Streptococcus pyogenes/classificationABSTRACT
BACKGROUND: The role of non-tuberculous mycobacteria (NTM) as aetiological agents in the causation of lung infections has seldom been systematically studied from India. METHODS: Prospective study of Species identification from mycobacterial isolates. RESULTS: A total of 22 isolates of mycobacteria were isolated from 635 samples of suspected tuberculosis in a two months period, of which 17 were Mycobacterium tuberculosis, three Mycobacterium kansasii and one each of Mycobacterium fortuitum and Mycobacterium gordonae. CONCLUSIONS: This study highlights the importance of NTM as potential pathogens from both pulmonary and extrapulmonary sites in the Southern state of Pondicherry. Further studies on a larger scale are needed to delineate clearly the association of NTM and various infections, especially in immunocompromised patients.
Subject(s)
Adolescent , Adult , Child , Humans , India , Middle Aged , Nontuberculous Mycobacteria/isolation & purification , Mycobacterium Infections, Nontuberculous/diagnosisABSTRACT
Cryptococcus neoformans has emerged as an important opportunistic fungal pathogen in immunocompromised individuals. The therapeutic options of C. neoformans an opportunistic fungal pathogen include flucytosine, amphotericin B, and azole agents. However in the present scenario, emergence of resistance has been reported, hence this study was undertaken to evaluate antifungal susceptibility pattern of C. neoformans isolates from this southern part of India. Ten isolates of C. neoformans were tested against Amp B and fluconazole, of which 7 were susceptible to both and a single isolate of C. neoformans var gatti was resistant to both with MIC of 32mg/ml and 64mg/ml respectively.