Pathologie developpementale du langage oral

Introduction et objectif : La pathologie developpementale du langage oral est une entite nosologique dont l'etiologie est multiforme. Cette etude avait pour objectif d'en determiner les caracteristiques epidemiologique et clinique a Abidjan. Population et methodes : cette etude retrospective et descriptive a ete realisee au CHU de Cocody et a l'institut national de sante publique ; de 2000 a 2006 (07ans). Resultats : 173 enfants parmi 1942 presentaient un trouble du langage oral (8;9). 124 enfants ont ete inclus dans l'etude. Leur age moyen etait de 3;4 ans. Il y avait 53 garcons pour 71 filles. Les motifs de consultation etaient domines par le retard de langage (39;5). Des antecedents pathologiques ont ete releves : la prematurite (5;64); la souffrance cerebrale (14;51); la meningite (5;64) et les convulsions non febriles (11;29). Ces troubles du langage etaient secondaires (46) a une affection otologique (23;4) ou neurologique (11;3). Conclusion : la pathologie developpementale du langage oral est frequente a Abidjan. Sa prise en charge doit etre codifiee afin de la rendre plus efficace

Effect of aqueous extract of boerhavia diffusa leaves on the glycaemia of rabbits.

Diabetes touches approximately 5% of Côte-d’Ivoire population. This is a worrying prevalence rate. Our search for means of fighting this affection made us to develop an herbal medicine from decoction of Boerhavia diffusa leaves. An ethnopharmacological survey conducted in villages of Côted’Ivoire, made us discovered that Boerhavia diffusa is used by traditional healers as antidiabetic. In Laboratory, during the experience we carried out, rabbits received, orally, a solution of glucose (4 g/l). Before administration of glucose, the animals had a basal glycaemia of 1.11 ± 0.04 g/l. The not treated rabbits’ glycaemia increased and reached 1.39 g/l. The oral administration of glibenclamide lowers blood sugar at about 0.86 g/l, after 180 minutes. The others hyperglycaemic rabbits were given herbal medicine to drink, 0.6 ml per 20 grams of body weight. At 2.5 mg/ml, the phytomedicine does not induce hypoglycaemic effect. At 10 mg/ml, it makes the hyperglycaemia go down from 1.17 g/l to 0.91 g/l. At 40 mg/ml, it induces a significant decrease in blood glucose. A fall of 34 % was observed, 180 minutes later. The glibenclamide exerts a significant basal glucose-lowering effect. The herbal medicine exerts on basal glycaemia a deep action and can induce, at 40 mg/ml, a hypoglycaemic coma. The effect of herbal medicine (40 mg/ml) on hyperglycaemic rabbits is compared to glibenclamide (0.25 mg/ml). The herbal medicine has a hypoglycemic effect and appears like an antidiabetic and produces its hypoglycaemic effect mainly through alkaloids, sterols or triterpens.