ABSTRACT
A 76-year-old man received implantation of sirolimus-eluting stent for total occlusion of the left circumflex artery causing an acute myocardial infarction of posterolateral wall on May 21st, 2005. Off-pump coronary artery bypass grafting was performed on June 9th for a residual 90% stenosis on the proximal segment of his left anterior descending artery. Ticlopidine and aspirin were discontinued 7 days and 2 days before the operation, respectively. Continuous intravenous drip of heparin had been given for 5 days until just prior to the operation. Though the left internal thoracic artery was successfully grafted onto the left anterior descending artery, he developed an acute myocardial infarction after the operation. An emergency angiography, performed on the 1st postoperative day showed thrombotic occlusion of the sirolimus-eluting stent in the circumflex artery and patent internal thoracic artery to the left anterior descending artery. Percutaneous catheter intervention restored the stent patency. Antiplatelet therapy including ticlopidine or clopidogrel is mandatory to prevent subacute thrombosis in drug-eluting stent. Hemorrhagic complication or major surgery may hinder continuing antiplatelet regimens and trigger acute thrombosis. Alternative antiplatelet and/or anticoagulant therapy is essential to prevent acute stent occlusion in such clinical settings.
ABSTRACT
Primary cardiac malignant lymphoma (PCL), which is defined as an extra-nodal malignant lymphoma involving only the heart and/or pericardium, is extremely rare. Its prognosis is reported to be very poor because the PCL grows rapidly and frequently causes fatal heart failure or arrhythmias. We report a 65-year-old woman with PCL accompanied with superior vena cava (SVC) syndrome 6 weeks following a pacemaker implantation for complete atrio-ventricular block. She underwent a partial resection of the tumor to release the SVC syndrome and subsequent systemic chemotherapy. This combined therapy successfully induced complete remission, and improvement of the atrio-ventricular conduction disturbance was also observed.
ABSTRACT
Left ventricular noncompaction (LVNC) is believed to represent an arrest in the normal process of myocardial compaction, resulting in persistence of both hyper-trabeculation and intratrabecular recess within the left ventricle. High mortality is the important clinical feature of this disease. LVNC in adult cases has been rarely, but occasionally, reported, however, LVNC with insufficiency of both the aortic and mitral valves has not been reported to our knowledge. Herein, we describe a 62-year-old man with LVNC and the severe insufficiency of the aortic and mitral valves, who was successfully operated upon with aortic and mitral valve replacement using mechanical valves. Although the postoperative course was uneventful, careful attention is mandatory for the possible left ventricular dysfunction due to LVNC.