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1.
Urology Annals. 2015; 7 (1): 58-62
in English | IMEMR | ID: emr-154907

ABSTRACT

The purpose of this study is to compare the perioperative total prostate specific antigen [tPSA] levels among coronary artery bypass grafting [CABG] patients with and without extracorporeal circulation [ECC], to investigate the changes overtime of tPSA in each group separately and to determine the effect of body core temperature on tPSA levels.A prospective study was conducted. Our sample was allocated to: [a] Seven patients who underwent off pump CABG [Group I] and [b] 16 CABG patients with ECC [Group II]. The levels of tPSA were measured preoperatively [baseline], intra-operatively and at the 4[th] postoperative day. We compared the two groups on their tPSA levels and we investigated the changes of tPSA overtime in each group separately. Intra-operative serum samples were obtained in significantly lower body temperature in patients of Group II than in those of Group I [31°C vs. 36.9°C, P < 0.001]. In each group separately, postoperative tPSA levels were increased significantly compared to the baseline values [2.55 ng/ml vs. 0.39 ng/ml for Group I, P= 0.005 and 4.36 ng/ml vs. 0.77 for Group II, P < 0.001]. CABG patients with ECC had significantly lower intra-operative tPSA levels than the baseline values [0.67 ng/ml vs. 0.77 ng/ml, P = 0.008]. We did not observe significant differences of tPSA levels between the two groups.CABG surgery affects similarly the perioperative tPSA independently the involvement of ECC. Although all patients had significantly higher early postoperative tPSA levels, only those who underwent CABG with ECC had exceeded normal values and significantly decreased intra-operative tPSA. Hypothermia seems to be the causal factor of tPSA reduction


Subject(s)
Humans , Male , Coronary Artery Bypass , Extracorporeal Circulation , Body Temperature , Perioperative Care , Prospective Studies , Hypothermia
2.
Annals of Thoracic Medicine. 2014; 9 (1): 8-13
in English | IMEMR | ID: emr-139563

ABSTRACT

Readmission in the intensive care unit [CU] is a significant morbidity index, which has been related to poor patient outcomes. To identify the preoperative and intraoperative risk factors for readmission in the cardiac surgery ICU. We conducted a retrospective cohort study of 595 consecutive patients who were admitted to the cardiac surgery ICU of a tertiary hospital of Athens - Greece during the one-year period [September 2011-September 2012]. Data collection was carried out, retrospectively, by the use of a short questionnaire and based on the review of medical and nursing patient records at December 2012. The incidence of ICU readmission was 3.7% [22/595]. Respiratory disorders were the main reason for readmission [45.4%]. Readmitted patients had a significantly higher in-hospital mortality compared to those requiring no readmission [P< 0.001]. Multivariate analysis revealed that female gender [for males odds ratio [OR] 0.37, 95% confidence interval [Cl] 0.15-0.89], high logistic EuroSCORE [OR 1.02, 95% Cl 1.00-1.04], prolonged cardiopulmonary [CPB] duration [OR 1.01, 95% Cl 1.00-1.02] and preoperative renal failure [OR 1.02, 95% Cl 1.00-1.05] were the independent risk factors for readmission to the cardiac surgery ICU. One intraoperative and three preoperative variables are associated strongly with higher probability for ICU readmission. Shorter CPB duration could contribute to lower ICU readmission incidence. In addition, the early identification of high risk patients for readmission in the cardiac surgery ICU could encourage both the more efficient healthcare planning and resources allocation


Subject(s)
Humans , Male , Female , Coronary Artery Bypass , Intensive Care Units , Incidence , Length of Stay , Surveys and Questionnaires , Cohort Studies , Retrospective Studies , Hospital Mortality
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