ABSTRACT
The level of glucose, uric acid, cholesterol triglycerides and transminase (SGOT and SGPT) and also hematological data of hematocrit and white cell count of 1,542 workers age ranging from 35-53 years who came for physical check up during B.E. 2532 – 2534 were analysed for the groups of smokers, drinkers and smokers together with drinkers. All the three groups have significantly high level of biochemistry substances, hematocrit and white cell count than normal group (p < 0.005) except HDL-Cholesterol which is significantly lower than the normal group (p < 0.005). However, the white cell count of habitual drinkers and cholesterol level in smokers together with drinkers have no significantly different from the normal. We categorie the number of cigarette smoked by both questionnaires and the thiocyanate levels, and found the serum thiocyanate levels correlates with the number of cigarette smoked (p < 0.001).