Comparison between effectiveness of topical 1% lindane cream and oral ivermectin in the management of scabies

To compare the efficacy of lindane 1% cream with oral ivermectin in the management of scabies. Interventional quasi-experimental study. This study was conducted in Dermatology Department of Nishter Hospital Multan, from 1[st] November 2005 to 31[st] April 2006. One hundred Patients; diagndsed for scabies by history [nocturnal itch], dermatological examination [papules, vesicles, burrows] and parasitological examination under microscope, selected by convenient sampling, were randomly assigned into two groups. Group-A was given 1% lindane cream and to Group B was given ivermectin. Both groups were treated with 2 doses after interval of 1 week, 11 out of these were dropped later on, so 89 patients, 45 in ivermectin group and 44 in lindane group were accessed for final results. Cure criteria for comparison of two treatments was absence of nocturnal itch, papules, vesicles, burrows and mite/ova under M/S. At day 8, 69% in group-B were completely cured as compared to 57% in group-A. P value was 0.00. At day 15, in group-B 91% were completely cured as compared to 86% in group-A. [P = 0.00]. At day 30, 100% in group-B were cured as compared to 89% in group-A. P=. 0.00. Oral ivermectin was significantly more effective than lindane 1% cream in treatment of scabies

Cutaneus manifestations of diabetes in diabetic patient presenting in outdoor

The aim of our study was to evaluate the frequency of skin manifestations in diabetic patients. Cross sectional study. Outpatient Department of Nishter Hospital Multan during the period from 1-6-2006 to 1-6-2007. One hundred and fifty-one type-2 diabetic patients [106 women and 45 men] attending an outpatient clinic were included in this study. All patients were then asked about any skin problems they might have and subsequently all were examined, regardless of their response. A total of 36 dermatologic disease entities were categorized. Information regarding age, sex, and the presenting disorders was recorded. The overall prevalence of one or more identifiable/apparent skin conditions was 85.4%. The most common skin conditions were infections [31.7%] [mostly mycoses], non-Candidal intertrigo [20.5%], eczemas [15.2%] [mostly neurodermatitis], psoriasis [11.2%], diabetic dermopathy [11.2%], and prurigo [9.9%]. According to sex, there was no significant difference in the prevalence of skin disorders. This study shows that skin cenditions are common in patients with type-2 diabetes mellitus. Therefore, frequent dermatologic evaluation of these diabetic patients is warranted