ABSTRACT
The present investigation involves antimicrobial and phytochemical evaluation of Cissus quadrangularis L. The antibacterial activity of Cissus quadrangularis was performed using disk diffusion method. The Results of study proved prompt efficacy of herbal extract against S. aureus and E. coli. The concentration dependent antibacterial activity of extract was observed against both organisms. Study also involves phytochemical investigation of herbal extract using HPTLC, IR and UV-Visible spectrophotometer. The result of study indicated that the methanolic extract possessed most potent antibacterial activity as compared to other extract. The antibacterial activity increases with the concentration and results indicated that the diameters of zone inhibition of the extract were comparable with the standard drug. The antimicrobial potential of plant extract may be attributed to the presence of specific phytoconstituents.
ABSTRACT
Psoriasis is one of the commonest skin disorders seen in routine clinical scenario, in entire world around 80 million people suffering from psoriasis. Psoriasis is differentiated by patches of abnormal skin. These skin patches are typically red, itchy, and scaly. Psoriasis varies in severity from small, localized patches to complete body coverage. It typically presents as red patches with white scales on top. Areas of the body most commonly affected are the back of the forearms, chin, navel area, and scalp. Diagnosis is typically based on the signs and symptoms. Men and women are affected with equal frequency. The disease may begin at any age, but typically starts in adulthood. Psoriasis is associated with an increased risk of psoriatic arthritis, lymphomas, cardiovascular disease and depression. Psoriatic arthritis affects up to 30 percent of individuals with Psoriasis. It is noted that around 2% of population are touching with Psoriasis. In present study review on Herbs frequently used in treating psoriasis were compiled. The Herbs Nimba, Stri Kutaja, Guduchi, Daruharidra, Bhallataka Haritaki, Aragvadha, Amalaki, Karveera, Saptaparna, Khadira, Vasa, Guggulu, Chitraka & Katuki are reviewed to be having Vata or Kapha balancing properties. The pharmacological studies showing that Nimbidin of Neem having anti psoriatic property, The Methanolic and ethanolic extracts of Stri Kutaja and Guduchi are having anti oxidant and anti psychotic properties which are helpful in reducing the symptoms of psoriasis.