Research progress of janus kinase - Signal transducers and activators of transcription signal transduction pathway and neurogenesis / 解剖学报

Janus kinase-signal transducers and activators of transcription (JAK-STAT) signal transduction pathway is related to cellular biological activities and occurrence and development of many diseases. In recent years, JAK-STAT signal transduction pathway has been found in the central nervous system to regulate neurodegenerative diseases and nerve regeneration after nerve injury: however, promoting endogenous neurogenesis as a new direction of nerve regeneration research is also closely related to the positive or negative regulation of JAK-STAT signal transduction pathway. This article reviews the research progress of JAK-STAT signal transduction pathway, neurogenesis, and JAK-STAT signal transduction pathway regulating neurogenesis.