A rare case of Pleuropulmonary blastoma type III with Immunohistochemical Study

Here we intend to document a rare case of PPB type III in a 2-year male presenting with an extensive tumor occupying the right hemithorax with immunohistochemical (IHC) study. Pleuropulmonary blastoma (PPB) is a rare variably aggressive, dysodontogenetic, childhood primary intrathoracic malignancy which in up to 25% of cases can be extrapulmonary with attachment to the parietal pleura. It is found in pediatric population under 5 years of age. It was initially proposed as a distinct entity by Manivel et al. in 1988. PPB is a proliferation of primitive mesenchymal cells that initially form air-filled cysts lined by benign-appearing epithelium (type I, cystic). Later on, the mesenchymal cells outgrow the cysts with formation of focal solid areas (type II, solid and cystic) and finally, mainly solid mass (type III, solid PPB).

A rare case of primary giant myxoid liposarcoma of the pericardium

Primary pericardial neoplasms account for 6.7–12.8% of all primary tumors arising in the cardiac region. Pericardial tumors are most likely to be metastatic and are an extension of the primary tumors from the surrounding structures. Sarcomas of the pericardium are rare. Myxoid liposarcoma (ML) represents about 5% of all the soft-tissue sarcomas in adults. They are usually located in the deep soft tissues of the extremities. There have been less than 20 cases of pericardial liposarcomas reported on PubMed since 1973. Here, we present a rare case of primary giant pericardial myxoid liposarcoma (ML) in a 46-year-old female diagnosed on frozen section and later was confirmed histopathologically.

Microbial Composition of Smokeless Tobacco Products from Karnataka

Background: Though there is a lot of literature available about presence of carcinogenic chemicals in these products, there is lack of information regarding the microbial composition of these products. Aim & Objective: The study was conducted with the objective of assessing microbial composition of smokeless tobacco products and factors associated with higher colony count. Methodology: This cross sectional study included a total of 43 samples obtained from four districts of Karnataka namely Udupi, Bengaluru, Bidar and Belagavi. Microbial populations were assessed using quantitative aerobic culture and colony forming units per gram was reported for each sample. The data was entered into excel and analysed using Statistical Package for Social Sciences version 16.0. Results have been expressed as frequencies and percentages. Univarate analysis was done to study association between background characteristics and higher colony counts. Results: All except three samples showed bacterial contamination. Two samples showed pathogenic bacterial growth, while the other 38 samples had non-pathogenic bacteria. There was no association between background characteristics and colony counts. Conclusions: Microbial contamination of smokeless tobacco products is common. There is a need to further investigate various factors associated with microbial contamination so that necessary interventions can be implemented.