ABSTRACT
Background: Sport science studies applications of scientifi c principles and techniques with the aim of improving sports performance. Objective: Present research work was carried out with the aim to enhance the sport performance of children. Materials and Methods: Randomized double blind placebo controlled study was conducted in children involved in sports to assess the effi cacy of trial drug “Vidarikandadi Yog”. Total of 72 healthy students were selected for the study after screening 412 students. Out of them, 60 students completed the study. The students were randomly divided into two groups. Group A (Vidarikandadi Yog) comprising of 38 and Group B (placebo) of 34 students. The trial drug “Vidarikandadi Yog” was given in the dose of 200 mg/kg/day in two divided doses for 2 months with milk and follow up was conducted fortnightly. Results: The study revealed the statistically signifi cant results for weight and chest circumference, whereas highly signifi cant results were obtained for muscular strength and endurance assessment parameters (Push-up Test, Sit-up Test, and Hand Grip Strength Test). Change in Ruler Drop Test was not signifi cant. Results were signifi cant for cardio-respiratory parameters (Resting Heart Rate, Resting Respiratory Rate, and Harvard Step Test). Conclusion: Vidarikandadi Yog is a potential drug for enhancing the sport performance due to its Brinhaneeya effect.
ABSTRACT
Context: Nutritional iron deficiency is the most common cause of anemia in India. The nearest correlation of iron deficiency anemia (IDA) can be made with Pandu Roga in Ayurveda. As the IDA is a very common prevalent disease in the society and the side effects of oral allopathic iron preparations are very common, therefore to get a better alternative, an Ayurvedic herbomineral medicine, the Trikatrayadi Lauha, was subjected to a clinical trial in children suffering from IDA. Aim: Evaluation of safety and efficacy of the compound Trikatrayadi Lauha suspension in children with IDA. Settings and Design: Randomized, double-blind placebo-controlled clinical study. Materials and Methods: The study was conducted on 123 children of IDA for a period of 10 weeks. Clinical features and hematological parameters were documented before, during and after treatment. Statistical Analysis Used: Observations of the study were analyzed and findings were evaluated by using statistical methods (Student's t test) Results: The present study shows that the trial drug Trikatrayadi Lauha suspension is effective to improve clinical features and hematological parameters significantly. The medicine is effective to increase the hemoglobin level 1.94 g/dL (8.52 -10.46 g/dL, P < 0.001) in 5 weeks and 3.33g/dL (8.52 -11.85g/dL, P < 0.001) in 10 weeks. No adverse effect of the trial drug was observed during the study. Conclusions: The results suggest that Trikatrayadi Lauha is significantly effective in the management of IDA in children.