ABSTRACT
Background: To compare the safety and efficacy of Macintosh, McCoy and Truview laryngoscope in simulated difficult laryngoscopy using rigid neck collar in overweight patients. Methods: It was a Prospective, randomized, controlled clinical trial conducted in a tertiary care teaching hospital. Overweight patients (BMI= 25-29.9) with American Society of Anesthesiologists physical status I and II, age 18 to 60 years and scheduled recruited for elective surgery requiring general anesthesia with oral endotracheal intubation were included. The patients were divided into three groups comprising of 40 patients each in which Macintosh, McCoy and Truview laryngoscopes were used respectively. Difficult laryngoscopy was simulated using rigid neck collar. The primary outcome measure was modified Intubation Difficulty Score (IDS ). The secondary outcome measures were number of attempts, ease of intubation, overall success rate, time of intubation, Percentage of Glottic Opening score, hemodynamic parameters and complications. Results: The mean Intubation Difficulty Score was significantly lower with Truview Laryngoscope (1.68) as compared to Macintosh (4.21)and MacCoy (3.03) laryngoscopes. The median Percentage of Glottic Opening score was also significantly improved in the Truview group(78.21) compared to the other groups. Number of successful first intubation attempt was significantly higher in the Truview group(63.16%) compared to the other groups. The overall success rate was similar among groups. However, the time of intubation was significantly higher for Truview (41.21±2 sec) compared to Macintosh and McCoy laryngoscopes. Conclusion: The Truview laryngoscope allowed better glottic visualization, greater ease of intubation, fewer intubation attempts, but a longer intubation time compared to Macintosh and MacCoy laryngoscopes.
ABSTRACT
Promoter regions in the genomes of all domains of life show similar trends in several structural properties such as stability, bendability, curvature, etc. In current study we analysed the stability and bendability of various classes of promoter regions (based on the recent identification of different classes of transcription start sites) of Helicobacter pylori 26695 strain. It is found that primary TSS and operon-associated TSS promoters show significantly strong features in their promoter regions. DNA free-energy-based promoter prediction tool PromPredict was used to annotate promoters of different classes, and very high recall values (~80%) are obtained for primary TSS. Orthologous genes from other strains of H. pylori show conservation of structural properties in promoter regions as well as coding regions. PromPredict annotates promoters of orthologous genes with very high recall and precision.
ABSTRACT
The study reports the prevalence of non-conducive behavioural practices in the area of “health care” prevalent in 1134 families of Northern India. Sample consisted of 563 families from rural and 571 families from urban area of Barabanki (Centre), Muzaffarnagar (North) & Gorakhpur (East) district of Uttar Pradesh, India. Behaviour correlates in the area of health care were mapped on a pre-prepared schedule, “Proforma for mapping of Behaviour correlates”. Percentage, hypothesis testing for difference between proportions and rank-order correlation was used for statistical analysis of data. Findings suggest that significantly more families from rural areas were involved in non-health conducive behavioral practices in all the studied constituent elements of self care except ‘carefulness about oral hygiene’. Urban families were more frequently involved in regular daily routine, carefulness about personal hygiene, appropriate use of personal & leisure time activities, elderly & child care than rural area. The study highlights the need for behavioural intervention both in urban as well as rural families in day to day living.
Subject(s)
Adult , Aged , Child , Delivery of Health Care , Health Behavior/psychology , Health Promotion/methods , Humans , India , Rural Population , Urban PopulationABSTRACT
BACKGROUND & OBJECTIVES: The commonly used available scales for measurement of socio-economic status (SES) with some cross regional applicability are old and have lost their relevance. There is a need for the development of a valid and reliable instrument for measurement of SES in rural and urban communities in India. The present study was undertaken to develop a cross regionally applicable scale for the purpose of enlisting true measures of socio-economic items applicable in multilingual, multicultural, multireligious, setting of the country. METHODS: For developing the scale, seven indicators (house, materials possession, education, occupation, monthly income, land, social participation and understanding), presumably determining the socioeconomic status were selected. These indicators were named as profiles. Thus, initially the scale had seven profiles and every profile contained five alternatives. This instrument was prepared on a 10-point scale. Weightage system of scoring (varying from 2 to 10) was followed from first to sixth profile while the additive pattern of scoring was followed in seventh profile. The final version of the scale was arrived at through three trial administrations on rural and urban families. The basis of selection of the families for the first two trials was stratified random. The validity and reliability of the scale was established through a defined visual analogue scale (VAS) and test-retest methods. RESULTS: Both the initial version as well as the final version of the scale for the measurement of SES of incumbents had seven profiles. The difference between the two versions was in terms of contents and range of items in different categories of SES. The final version was arrived at through field trials and suggestions of the experts. The reliability of the scale was high with a correlation coefficient of 0.998. INTERPRETATION & CONCLUSION: The new scale appears to be a valid and reliable instrument for the assessment of socio-economic status of the families/individuals from urban as well as rural areas in India.