ABSTRACT
A field experiment was conducted during rabi 2022 at Block D of the College Farm, Agriculture College, Naira. The experiment was laid out in Split-plot design with three main plots.M1:100% RDF (180-60-60 NPK Kg ha-1) + FYM @10 t ha-1, M2:75% RDF (135-45-45 NPK Kg ha-1) + FYM @10 t ha-1. M3:0% RDF- Control and four sub-plotsS1: Liquid azospirllum+PSB+KRB+ZnSB+@1.25 L ha-1 each at knee high stage, S2: Vermiwash spraying twice @5% at knee high and tasseling to silking stages, S3: Panchagavya spraying twice @3% at knee high and tasseling to silking stages andS4: Drava Jeevamrutham spraying twice @10% at knee high and tasseling to silking stages Results revealed that 100% RDF (180-60-60 NPK Kg ha-1) + FYM @10 t ha-1 (M1) recorded maximum fresh cob yield (16409 kg ha-1) and stover yield (17481 kg ha-1). Among the subplots: Liquid azospirllum+ PSB+ KRB+ ZnSB+@1.25 L ha-1 (S1) recorded maximum fresh cob yield (14091 kg ha-1) and stover yield (15623 kg ha-1). The interaction effect of different doses of RDF and liquid biofertilizers on fresh cob yield, stover yield and HI was found to be nonsignificant. Hence, it can be concluded that different doses of RDF and liquid biofertilizers are advantageous for weet corn cultivation on sandy loam soils of North costal region.
ABSTRACT
Acute-on-chronic liver failure is an acute deterioration of liver function manifesting as jaundice and coagulopathy with the development of ascites, with a high probability of extrahepatic organ involvement and high 28-day mortality. The pathogenesis involves extensive hepatic necrosis, which is associated with severe systemic inflammation and subsequently causes the cytokine storm, leading to portal hypertension, organ dysfunction, and organ failure. These patients have increased gut permeability, releasing lipopolysaccharide (LPS) and damage-associated molecular patterns (DAMPS) in the blood, leading to hyper-immune activation and the secretion of cytokines, followed by immune paralysis, causing the development of infections and organ failure in a proportion of patients. Early detection and the institution of treatment, especially in the "Golden Window" period of 7 days, gives an opportunity for reversal of the syndrome. Scores like the Asian Pacific Association for the Study of the Liver (APASL) ACLF research consortium (AARC) score, a model for end stage liver disease (MELD), and the CLIF Consortium acute-on-chronic liver failure (CLIF-C ACLF) score can help in the prediction of mortality. Treatment strategy includes treatment of acute insult. Patients should be considered for early transplant with MELD score >28, AARC score >10, high-grade hepatic encephalopathy, and in the absence of >2 organ failure or overt sepsis to improve survival of up to 80% at five years. Patients, with no option of transplant, can be treated with emerging therapies like faecal microbial transplant, plasma exchange, etc., which need further evaluation.