ABSTRACT
Successful management of parturition induction is a challenging task in canine. This study made to assess the efficacy of antiprogestagen mifepristone and prostaglandin misoprostol in induction of parturition in bitches. Total of 11 pregnant bitches with gestational age of more than 62 days confirmed by ultrasound scanning and not showing any sings of initiation of parturition were selected. Induction of parturition was initiated by mifepristone (3 mg/ kg b wt PO) twice a day or a combination of mifepristone (3 mg/kg b wt PO) and misoprostol (200 ?g for < 20 kg, 400 ?g for > 20 kg b wt, i/vg) 12 h after second dose of mifepristone. The combination of both drugs mifepristone and misoprostol was more effective for parturition induction.
ABSTRACT
Canine pyometra is an acute or chronic polysystemic diestrual disorder mainly of mature nulliparous bitches. In this retrospective study, an attempt was made to analyse the physiological and haemato-biochemical parameters of a total of 22 affected bitches attended at Sneh Vet lab and Clinic Bhadra, Bhiwani, (Haryana). The findings revealed pyrexia and tachycardia with normal respiration rate in most of the pyometra affected bitches. Amongst the haemato-biochemical parameters, there were reduced levels of haemoglobin, packed cell volume and total erythrocyte count, along with severe leucocytosis, neutrophilia with shift to left, lymphopenia, eosinophilia and elevated BUN and serum creatinine in the bitches affected with pyometra suggesting bone marrow and renal damage. However, the mean values of mean corpuscular volume, mean corpuscular haemoglobin as well as serum ALT and AST were within the normal range, confirming normocytic normochromic anaemia without liver dysfunction.
ABSTRACT
A nondescript cattle was reported to dystocia with twin foetus that cause the impaction of maternal pelvis, after lubrication and obstetrical procedure per vaginal both fetus was expelled live with no complication.
ABSTRACT
Decidual cast is the entire sloughed endometrium that takes the form of the endometrial cavity. It causes membranous dysmenorrhea because the intact cast passes through an undiluted cervix. It may be associated with ectopic pregnancy, incomplete abortion, non-pregnant state with use of progesterone, Depot medroxyprogesterone acetate (DMPA), rarely with oral contraceptive pills. Authors are reporting a case of recurrent decidual caste formation with membranous dysmenorrhoea in 33 years old women P3L3 who was on norethisterone acetate treatment for a typical uterine bleed (AUB). She presented with heavy menstrual bleeding with severe dysmenorrhea in Gynae causality of ESI Basaidarapur medical college, Delhi. She expelled decidual caste and required therapeutic Dilation and Curettage (D and C) to control bleeding per vaginum. Her histopathology report showed marked decidua like change of the stroma but no villi suggestive of endometrial caste.
ABSTRACT
Background: There is a perception that Mefenamic Acid should be the preferred NSAID for menorrhagia. However, there are insufficient evidences to prove this. Further RCTs are required to compare individual NSAIDs.Purposes of the study were to assess and compare the efficacy of mefenamic acid and diclofenac in control of menorrhagia in patients with DUB, to assess and compare their analgesic effects in dysmenorrhea associated with DUB and to study their adverse effects.Methods: Sixty-eight patients were randomized into either Mefenamic Acid (n=34) or Diclofenac (n=34) group. Efficacy variables (Pictorial Blood loss Assessment Chart quantification, Number of pads used, Number of days of menstrual bleeding, Visual Analog Scale score) and adverse effects were recorded over three menstrual cycles.Results: The median reduction of menorrhagia with Mefenamic Acid was 43.39% (Range: 2.86% to 94.4%) and for Diclofenac was 57.5% (Range: 9.9% to 93.58%). The Diclofenac group showed a statistically significant decrease in median bleeding volume, median number of pads used and median number of days of bleeding compared to the Mefenamic Acid group (p<0.05, CI = 95%) but did not show a statistically significant decrease in median VAS score compared to the Mefenamic Acid group. Adverse effects with both groups were mild.Conclusions: Mefenamic Acid and Diclofenac individually managed to significantly reduce excessive bleeding compared to baseline. Diclofenac fared better than Mefenamic Acid in terms of control of excessive menstrual bleeding. Both these agents were able to reduce the menstrual pain and on comparison, were found to be equi-efficacious.