ABSTRACT
Background: Aim of current study was to know the etiological factors of jaundice among pregnant patients, outcome and their management. Methods: A retrospective study done at IMS, BHU in obstetrics and gynecology department among pregnant patients with jaundice admitted in obstetric wards and labour room in six months duration. Results: Among total 1960 admissions, 78 (3.97%) patients presented with jaundice. Out of all admissions 27 (1.37%) were HBSAg, 8 (0.40%) HEV, 7 (0.35%) HCV, 6 (0.30%) of HBSAg and HEV co-infection, cholestasis with pregnancy 20 (1%) and 10 (0.51%) patients with pre-eclamptic liver disease with HELLP. Conclusions: Jaundice in pregnancy may be lethal to mother and fetus. As the course of disease is also rapid and in short period it may affect the fetus in utero also, early detection and prompt management of these cases should be done.
ABSTRACT
A nine month old male child presenting degenerating right ulna (massive osteolysis) has been followed up for two years. The bone completely disappeared due to abscesses on the right forearm and without orthopedic or haematological complications. Repeated lymphocyte cultures showed somatic pairing (mostly chromosome pair 5), end to end association involving chromosome 14, 21, 21 and 16, and satellite enlargement in a high proportion of cells with an otherwise normal 46,XY karyotype. These observations are compared with 13 other types of orthopaedic patients, and we opine that cumulative picture of chromosomal aberrations appears to correspond with the present rare anomaly "Mono Ostolic Osteolysis" involving right ulna. None of the controls or any other orthopaedic anomaly studied hereunder exhibits this chromosomal picture.