ABSTRACT
Background: Extra-axial tumors are the most common adult intracranial neoplasms. Meningiomas are the most common Extra-axial tumors. Their Clinical presentation, survival rates, and prognosis vary depending on the site and specific type of tumor, hence necessitating a detailed clinical and radiological evaluation. Materials and methods: A prospective observational study on 15 symptomatic subjects who presented to a tertiary care hospital with Supratentorial intracranial tumors confirmed by CT was done. After getting a detailed history, clinical examination and CT (including contrast) were done. Results: In the study population, 73% had meningioma. 13% had a Pituitary Adenoma. 13% had craniopharyngioma. A headache was the most commonly reported symptom (73%). Majority of meningiomas were located in convexity of the brain (36.4%) and parasagittal areas (36.4 %). Conclusions: Neuroradiology plays a key role in the identification of supratentorial extra-axial tumors with CT allowing accurate anatomical description which can go a long way in management and defining prognosis.
ABSTRACT
Brucella melitensis is an organism of paramount zoonotic importance. The 28 kDa outer membrane protein (OMP) is one of the immunodominant antigens of B. melitensis. The gene encoding 28 kDa OMP (omp28) has been amplified from B. melitensis Rev. 1 strain. A PCR product of 753 bp, encoding complete omp28 gene of B. melitensis, was obtained. The gene was further cloned and sequenced. The nucleotide sequence of B. melitensis Rev. 1 strain showed substitution of 2 nucleotides from that of 16M strain.