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1.
Article in English | IMSEAR | ID: sea-163229

ABSTRACT

1KE8 is known as a potential target for anti-cancer medication. Indoles are biologically active nitrogen heterocyclics known for broad spectrum activities. Modification of Indole ring system with selected structural descriptors has offered a high degree of stereo specificity and diversity in activity to the moiety.


Subject(s)
Antineoplastic Agents/pharmacokinetics , Binding Sites , Computer Simulation , Cyclin-Dependent Kinase 8/metabolism , Heterocyclic Compounds, 2-Ring/pharmacokinetics , Indoles/classification , Indoles/pharmacokinetics , Molecular Docking Simulation , Molecular Dynamics Simulation
2.
Indian J Med Microbiol ; 2013 Jan-Mar; 31(1): 92
Article in English | IMSEAR | ID: sea-147559
5.
Indian J Dermatol Venereol Leprol ; 2001 Jan-Feb; 67(1): 31-2
Article in English | IMSEAR | ID: sea-52419

ABSTRACT

A case of polyneuritic leprosy is reported. There were minimal changes on skin, but changes in the bones were predominant. It is emphasized that polyneuritic leprosy is an entity. It is also stressed that neuritic leprosy can produce changes in deeper structures like bones, with minimal changes on skin.

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