Meta analysis of euthyrox on the blood lipid of patients with hypothyroidism / 中国生化药物杂志

Objective To study the effect of euthyrox on blood lipids in patients with hypothyroidism throngh the meta analysis.Methods Patients with clinical hypothyroidism theated by euthyrox on blood lipid effect of randomized controlled trials were retried by Pubmed(2000/2014-07),EMbase (2000/2014-07),the Cochrane library(2014,7),the Chinese biomedical literature database(2000/2014-07),retrieved the time limit from January 2000 to July 2014.The paper were objective evaluated of the quality,Meta analysis with Rev Man 5.3 software system applicated by Cochrane collaboration.Results Euthyrox could significantly reduce cholesterol levels of hypothyroidism patients ,it was statistically significant difference(OR=0.63,95%CI:0.71 ~0.55,P<0.001);Euthyrox could significantly reduce triglyceride levels of hypothyroidism patients,difference was statistically significant(OR =0.29,95%CI:0.34 ~0.25,P <0.001 );Euthyrox could significantly reduce low-density lipoprotein cholesterol levels of hypothyroidism patients,it was statistically significant difference(OR=0.22,95%CI:0.30 ~0.14,P<0.001);euthyrox could obviously increase high-density lipoprotein cholesterol levels, it was statistically significant difference (OR =0.21, 95% CI:0.17 ~0.26, P <0.001 ). Conclusion Euthyrox could significantly reduce total cholesterol,triglyceride,low-density lipoprotein cholesterol(hdl-c)of hypothyroidism patients,and promote the synthesis of high-density lipoprotein cholesterol(hdl-c),could effectively promote the lipid metabolism,reduce blood fat level,prevent the happening of the disease of heart head blood-vessel hypothyroidism patients,have the guide meaning to clinical treatment.

The etiological factor analysis and treatment of 98 hypokalemia cases in old people / 中国综合临床

Objective To analyze various etiological factors and treatment of hypokalemia in old people. Methods Clinical and chemical data of 98 hypokalemia cases were retrospectively analyzed. Results The main reasons leading to hypokalemia were hypertension (32.7%), heart failure (26.5%), diabetes(12.2%), hyperthy-roidism(10.2%),disease of digestive system(10.2%),severe infection(4.1%),oral disease (2.0%) and other diseases(2.0%). The treatment strategy focused on primary disease and oral or venous potassium. Conclusion Much emphasis should be put on analyzing the possible causes of hypokalemia in addition to rectifying the lack of po-taasium.