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Indian J Dermatol Venereol Leprol ; 2014 Jan-Feb; 80(1): 97
Article in English | IMSEAR | ID: sea-154791
4.
Indian J Dermatol Venereol Leprol ; 2006 Nov-Dec; 72(6): 440-2
Article in English | IMSEAR | ID: sea-52908

ABSTRACT

Chemotherapy-induced acral erythema is a painful erythema of the palms and soles which occurs following chemotherapy. It is usually seen due to cytarabine, doxorubicin and fluorouracil. We present a 40-year-old male patient, a biopsy proven case of squamous cell carcinoma of the floor of the mouth, who developed a bullous variant of acral erythema after a single intravenous dose of methotrexate. He also had fever, buccal mucositis, leucopenia, thrombocytopenia and hyperpigmented macular rash on the face and upper trunk. The bullous variant of acral erythema due to methotrexate has rarely been reported.


Subject(s)
Adult , Antimetabolites, Antineoplastic/adverse effects , Carcinoma, Squamous Cell/drug therapy , Drug Eruptions/pathology , Erythema/chemically induced , Foot , Hand , Humans , Injections, Intravenous , Male , Methotrexate/administration & dosage , Mouth Neoplasms/drug therapy , Stomatitis/chemically induced
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