ABSTRACT
Introduction: Centchroman is an effective oral contraceptive has a good patient acceptability and compliance due to its minimal side effects, low cost and simple dosage schedule. This study was undertaken to study the adverse drug reactions of centchroman used for contraceptive purpose. Material and Methods: The cases were selected from the patients attending post partum programme centre and outdoor department of Obstetrics and Gynaecology, at LLRM Medical college and associated hospital, Meerut, UP, who were taking non-hormonal oral contraceptives (centchroman) preparations for a period of twelve months. Women of reproductive age groups were included and asked not to use any other method of contraception during the study. Every Woman was asked to report immediately if she develops any problem after taking pills and asked for regular follow up at every month. Results: During the study period, a total of 25 women receiving centchroman for contraception were evaluated. The most common adverse drug reaction reported was menstrual irregularity. After 6 months of therapy, 40% women presented with this complain. 12% cases presented with other complaints in form of abdominal pain and giddiness. Conclusion: Non-hormonal oral contraceptives (centchroman) are quite safe regarding adverse effect but menstrual irregularities are the major limiting factor for its use as contraceptive.