Annual Report on External Quality Assessment in Blood Bank Tests in Korea (2009) / 임상검사와정도관리

BACKGROUND: We report here the results of surveys for external quality assessment of blood bank tests performed in 2009. METHODS: Survey specimens were sent three times to 488, 491 and 490 participant institutes, and the response rates for the 1st, 2nd and 3rd trial were 97.7%, 98.0%, and 98.0%, respectively. Test items for the surveys were ABO grouping, Rh (D) typing, crossmatching, direct antiglobulin test, antibody screening and antibody identification test. RESULTS: The average accuracy rates of ABO grouping and Rh typing were 99.6-100% and 98.5-100%, respectively. In crossmatching test, the accuracy rates were 99.3-99.8% for the compatible samples, 92.7-100% for the incompatible samples, and 92.6-93.1% for the samples which could be detected as incompatible only by antiglobulin method. The accuracy rates of direct antiglobulin test were 98.5-100% for negative samples and 98.1-98.8% for positive samples. The correctresults were reported by 98.0-100% of the surveyed institutions for antibody screening test and 82.9-100% for antibody identification test. Nineteen institutions gave repeatedly incorrect answers for crossmatching test. Eight institutions out of them gave incorrect answers for all the test specimens sent out 3 times last year. CONCLUSIONS: The overall results of this survey were good, however, it is required that the institutions where the incorrect results were reported should perform corrective actions for quality improvement.

Annual Report on External Quality Assessment in Blood Bank Tests in Korea (2008) / 임상검사와정도관리

We report here the results of surveys for external quality assessment of blood bank tests performed in 2008. Survey specimens were sent three times to 460, 470 and 473 participant institutes, and the response rates for the 1st, 2nd and 3rd trial were 97.6%, 97.7%, and 97.7%, respectively. Test items for the surveys were ABO grouping, Rh (D) typing, crossmatching, direct antiglobulin test, antibody screening and antibody identification test. The average accuracy rates of ABO grouping and Rh typing were 100% and 98.3-100%, respectively. In crossmatching test, the accuracy rates were 97.5-99.7% for the compatible samples, 92.4-99.2% for the incompatible samples, and 88.2-98.9% for the samples which could be detected as incompatible only by antiglobulin method. The accuracy rates of direct antiglobulin test were 98.4-99.7% for negative samples and 93.4-99.7% for positive samples. The correct results were reported by 99.6-100% of the surveyed institutions for antibody screening test and 98.2-100% for antibody identification test. Twenty-three institutions gave repeatedly incorrect answers for crossmatching test. Ten institutions out of them gave incorrect answers for all the test specimens sent out 3 times last year.

Annual Report on External Quality Assessment in Blood Bank Tests in Korea (2007) / 임상검사와정도관리

We report here the results of external quality assessment of blood bank tests performed in 2007. Survey specimens were sent three times to 448, 450, and 455 participant institutes, and the response rates were 99.3%, 97.3%, and 98.0%, respectively. Test items for the surveys were ABO grouping, Rh(D) typing, crossmatching, direct antiglobulin test, antibody screening and identification test. The average accuracy rates of ABO grouping and Rh typing were in the range of 99.5-100% and 98.9-100%, respectively. In crossmatching test, the accuracy rates were 96.0-97.1% for the compatible samples, 89.6-92.4% for the incompatible samples, and 89.6-92.4% for the samples which could be detected as incompatible only by antiglobulin method. The accuracy rates of direct antiglobulin test were 98.0-99.7% for negative samples and 96.3-99.0% for positive samples. The correct results were reported by 95.7-100% of the surveyed institutions for antibody screening test and 98.2-100% for identification test. Fifteen institutions gave repeatedly incorrect answers for crossmatching. Five institutions out of them gave incorrect answers for all the test specimens sent out 3 times last year.

Annual Report on External Quality Assessment in Blood Bank Tests in Korea (2007) / 임상검사와정도관리

We report here the results of external quality assessment of blood bank tests performed in 2007. Survey specimens were sent three times to 448, 450, and 455 participant institutes, and the response rates were 99.3%, 97.3%, and 98.0%, respectively. Test items for the surveys were ABO grouping, Rh(D) typing, crossmatching, direct antiglobulin test, antibody screening and identification test. The average accuracy rates of ABO grouping and Rh typing were in the range of 99.5-100% and 98.9-100%, respectively. In crossmatching test, the accuracy rates were 96.0-97.1% for the compatible samples, 89.6-92.4% for the incompatible samples, and 89.6-92.4% for the samples which could be detected as incompatible only by antiglobulin method. The accuracy rates of direct antiglobulin test were 98.0-99.7% for negative samples and 96.3-99.0% for positive samples. The correct results were reported by 95.7-100% of the surveyed institutions for antibody screening test and 98.2-100% for identification test. Fifteen institutions gave repeatedly incorrect answers for crossmatching. Five institutions out of them gave incorrect answers for all the test specimens sent out 3 times last year.

Annual Report on External Quality Assessment in Blood Bank Tests in Korea (2005) / 임상검사와정도관리

We report here the results of surveys for external quality assessment of blood bank tests performed in 2005. Response rates for the 1st, 2nd and 3rd trial were 97.0%, 96.8%, and 97.1% respectively. Test items for the surveys were ABO grouping, Rh(D) typing, crossmatching, direct antiglobulin test, antibody screening and identification test. The average accuracy rates of ABO grouping and Rh typing were in the range of 99.5-100% and 99.7-100% respectively. In crossmatching test, the accuracy rates were 94.3-98.2% for the compatible samples, 88.5-92.9% for the incompatible samples, and 88.5-92.9% for the samples which could be detected as incompatible only by antiglobulin method. The accuracy rates of direct antiglobulin test were 98.9-99.3% for negative samples and 89.2-96.9% for positive samples. The correct results were reported by 98.3-100% of the surveyed institutions for antibody screening test and 98.9-100% for identification test. Seventeen institutions gave repeatedly incorrect answers for crossmatching. Thirteen institutions out of them gave incorrect answers for all the test specimens sent out 3 times last year.

Annual Report on External Quality Assessment in Blood Bank Tests in Korea (2004) / 임상검사와정도관리

We report here the results of surveys for external quality assessment of blood bank tests performed in 2004. Response rates for the 1st, 2nd and 3rd trial were 96.4%, 96.8%, and 96.8%, respectively. Test items for the surveys were ABO grouping, Rh(D) typing, crossmatching, direct antiglobulin test, antibody screening and identification test. The average accuracy rates of ABO grouping and Rh typing were in the range of 100% and 100%, respectively. In crossmatching test, the accuracy rates were 96.2-97.8% for the compatible samples, 75.5-90.6% for the incompatible samples, and 75.5-90.6% for the samples which could be detected as incompatible only by antiglobulin method. The accuracy rates of direct antiglobulin test were 98.8-100% for negative samples and 87.3-98.8% for positive samples. The correct results were reported by 98.8-100% of the surveyed institutions for antibody screening test and 100% for identification test. Forty six institutions gave repeatedly incorrect answers for crossmatching. Nine institutions out of them gave incorrect answers for all the test specimens sent out 3 times last year.

Annual Report on External Quality Assessment in Blood Bank Tests in Korea (2003) / 임상검사와정도관리

We report here the results of surveys for external quality assessment of blood bank tests performed in 2003. Response rates for the 1st, 2nd and 3rd trial were 93.1%, 91.7%, and 90.1%, respectively. Test items for the surveys were ABO grouping, Rh(D) typing, crossmatching, direct antiglobulin test, antibody screening and identification test. The average accuracy rates of ABO grouping and Rh typing were in the range of 99.7-100% and 99.7-100%, respectively. In crossmatching test, the accuracy rates were 97.4-100% for the compatible samples, 83.4-100% for the incompatible samples, 87.2-92.4% for the samples which were incompatible in albumin phase, and 83.4-88.8% for the samples which could be detected as incompatible only by antiglobulin method. The accuracy rates of direct antiglobulin test were 97.9-99.6% for negative samples and 93.8-95.0% for positive samples. The correct results were reported from 95.9-100% of the surveyed institutions for antibody screening test and 98.8-100% for identification test. Forty six institutions gave repeatedly incorrect answers for crossmatching. Nine out of 46 institutions gave incorrect answers for all the test specimens sent out 3 times last year.

Annual Report on External Quality Assessment in Blood Bank Tests in Korea (2002) / 임상검사와정도관리

We report here the results of surveys for external quality assessment of blood bank tests performed in 2002. Response rates for the 1st, 2nd and 3rd trial were 91.0%, 91.6%, and 91.8%, respectively. Test items for the surveys were ABO grouping, Rh(D) typing, crossmatching, direct antiglobulin test, antibody screening and identification test. The average accuracy rates of ABO grouping and Rh typing were in the range of 99.4-100% and 97.4-100%, respectively. In crossmatching test, the accuracy rates were 92.5-98.3% for the compatible samples, 73.7-99.7% for the incompatible samples, 88.0% for the samples which were incompatible in albumin phase, and 73.7% for the samples which could be detected as incompatible only by antiglobulin method. The accuracy rates of direct antiglobulin test were 96.3-98.4% for negative samples and 95.9-97.0% for positive samples. The correct results were reported by 98.6-100% of the surveyed institutions for antibody screening test and 100% for identification test. Forty six institutions gave repeatedly incorrect answers for crossmatching. Nine institutions out of them gave incorrect answers for all the test specimens sent out 3 times last year.

Plasmapheresis in Recurrent Focal Segmental Glomerulosclerosis after Renal Transplantation / 대한신장학회잡지

Focal segmental glomerulosclerosis (FSGS) in pediatric age tends to progress to end stage renal disease and to recur after renal transplantation. And recurrence of FSGS after kidney transplantation results in the graft loss in above half of cases. An unknown circulating factor in serum and immunologic dysfunction may be responsible for the recurrence. So, plasmapheresis to remove the uncertain serum factor and high dose cyclosporin A to control the immunologic system have been tried as the therapeutic regimen. We experienced 5 patients with recurrent FSGS after transplantation and tried plasmapheresis and methyl prednisolone pulse therapy with high dose cyclosporin A for them. The patients were 2 girls and 3 boys, aged between 8 and 14 years. In all cases, the kidney was donated by living related donors. Recurrence of FSGS was detected by postop. 3 days. Plasmapheresis started within 1 week after recurrence in 4 cases, and 2 months in 1 case. Early plasmapheresis brought rapid and sustained remission in 2 cases without evidence of acute rejection and short-term partial response in remaining 3 cases. In conclusion, plasmapheresis with high dose cyclosporin A resulted in a good outcome in recurrent FSGS. And starting plasmapheresis as early, prior to irreversible glomerular scarring, as possible is important for immediate and long-term prognosis in recurrent FSGS after renal transplantation.