ABSTRACT
Preventive and therapeutic effects of egg yolk antibody, immunoglobulin Y (IgY), against canine parvovirus (CPV) was evaluated in 25 pups orally challenged with CPV-2a. Oral administration of IgY using powder, paste and coated paste delivery systems was compared. Each type of IgY was administered orally for 17 days from 3 days before challenge. The group of pups administered coated IgY showed mild symptoms such as a moderate decrease in total white blood cell count, no depression, vomiting and diarrhea when compared with other groups. The overall clinical score of the group of pups administered coated IgY was significantly lower than that of the challenge control group. However, mortality did not differ among groups because not all pups received symptomatic treatment. These results implied that oral treatment of coated IgY could improve therapeutic effects against CPV challenge if pups received symptomatic treatment.
Subject(s)
Administration, Oral , Chickens , Depression , Diarrhea , Egg Yolk , Enteritis , Immunoglobulins , Immunotherapy , Leukocyte Count , Mortality , Parvovirus, Canine , VomitingABSTRACT
Sometimes physicians and clinical pathologists find very high levels of alkaline phosphatase (ALP) activity in their patients. This condition is associated with transient, marked increase in serum ALP in healthy infants and children. It has also been described in adults. Clinical and biochemical features of transient hyperphosphatasemia in infancy and early childhood are reviewed in six patients that we have studied. The diagnosis is suggested by findings of increased activity of alkaline phosphatase in plasma, typically more than fivefold the upper reference value for adult, in a child under five years of age, without evidence of liver or bone disease. The condition is confirmed by the presence of a characteristic pattern of alkaline phosphatase isoenzymes and by the normalization of enzyme activity in plasma within approximately six months after the original observation. The etiology of the condition and possible mechanism of the elevated ALP is discussed.
Subject(s)
Adult , Child , Humans , Infant , Alkaline Phosphatase , Bone Diseases , Diagnosis , Isoenzymes , Liver , Plasma , Reference ValuesABSTRACT
Ulcerative colitis is a chronic relapsing inflammatory disease of the colonic and rectal mucosa, which affects children as well as adults. Inflammation caused by ulcerative colitis is limited to the colon and rectum, to the mucosa and submucosa, and is involved continuously, with varying degrees of ulceration, hemorrhage, edema, and regenerating epithelium. Ulcerative colitis most commonly presents with the onset of diarrhea, later associated with hematochezia, but usually without systemic signs of fever, weight loss, or hypoalbuminemia. Approximately 30% of cases have moderate signs of systemic illness. Although less commonly seen than in Crohn's disease, the first sign of ulcerative colitis may be growth failure characterized by decreased linear growth velocity. We experienced a case of ulcerative colitis with growth disturbance and treated with sulfasalazine. During follow up for a year, the symptoms subsided, and the height and weight increased.
Subject(s)
Adult , Child , Humans , Colitis, Ulcerative , Colon , Crohn Disease , Diarrhea , Edema , Epithelium , Fever , Follow-Up Studies , Gastrointestinal Hemorrhage , Hemorrhage , Hypoalbuminemia , Inflammation , Mucous Membrane , Rectum , Sulfasalazine , Ulcer , Weight LossABSTRACT
No abstract available.
Subject(s)
Hypopituitarism , Magnetic Resonance Imaging , Pituitary GlandABSTRACT
No abstract available.
Subject(s)
Blood Platelets , Electrophoresis, Polyacrylamide Gel , Membrane Glycoproteins , Membranes , ThrombastheniaABSTRACT
No abstract available.