ABSTRACT
No abstract available.
ABSTRACT
Many complications have been reported after ear surgery to treat chronic inflammation. These complications include facial nerve paralysis, perichondritis, injury of the dura or of the sigmoid sinus, cyst formation or mucocele in the healed mastoid cavity, and the recurrence of cholesteatoma, granulation tissue, or otorrhea. It might be believed that there could be no relation between ear surgery and spontaneous aneurysmal rupture, and only one other case of spontaneous aneurysmal rupture after ear surgery under general anesthesia has been previously reported in Korea. However, recently, the authors encountered a case of delayed spontaneous aneurysmal rupture 3 weeks after surgery. No problem was experienced during the operation, and it is suspected that an unidentified pre-existing aneurysm was responsible for the intracerebral hemorrhage.
Subject(s)
Anesthesia, General , Aneurysm , Cerebral Hemorrhage , Cholesteatoma , Colon, Sigmoid , Ear , Facial Nerve , Granulation Tissue , Inflammation , Korea , Mastoid , Mucocele , Otologic Surgical Procedures , Paralysis , Recurrence , RuptureABSTRACT
BACKGROUND AND OBJECTIVES: We investigated the expression of glucose uptake transporter-1 (GLUT-1) and epidermal growth factor receptor (EGFR) in the head and neck squamous cell cancer (HNSCC) and their influence on survival rate. We also aimed to demonstrate the relationships between the expressions of GLUT-1 and EGFR and the maximal standardized uptake values (mSUV) of fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET). SUBJECTS AND METHOD: Surgical specimens from 50 patients with HNSCC, who had undergone surgical intervention, were first processed for tissue array and then for immunochemistry for GLUT-1 and EGFR. Expressions of GLUT-1 and EGFR were analyzed according to the differentiation of tumor, T & N stage and invasiveness of the tumor etc. The relationship between PET-mSUV and the expressions of EGFR and GLUT-1 was evaluated as well as its possibility as a prognostic factor of SUV. RESULTS: The expression of EGFR was significantly high in the lymph node of the positive group. Associated with the expression of GLUT-1, a tendency of increased index score (IS) values in the advanced T stages was observed but it was not statistically significant. The mSUV in FDG-PET showed statistically significant association with the maximal tumor size (pearson correlation 0.569, p=0.023); however, no association with GLUT-1 and EGFR was observed. A universal strong expression of GLUT-1 could have made it difficult to figure out statistically significant correlations. Disease free survival was to be influenced by T stage, moderate and poor differentiation and GLUT-1 expression. Only the T stages had independent significance in the multivariate analysis using the Cox regression model. CONCLUSION: We found that the expression of GLUT-1 could not show statistically significant correlation with PET-mSUV. Since the expression of EGFR has significant correlation with lymph node metastasis, EGFR may have the possibility of being a target for anticancer molecular therapy.
Subject(s)
Humans , Collodion , Disease-Free Survival , Glucose , Head , Immunochemistry , Lymph Nodes , Multivariate Analysis , Neck , Neoplasm Metastasis , Neoplasms, Squamous Cell , Positron-Emission Tomography , ErbB Receptors , Recurrent Laryngeal Nerve , Survival Rate , Thyroid GlandABSTRACT
We report two cases of reruptured anterior communicating artery aneurysm during cerebral angiography in one aged 80 years and the other aged 59 years. Both patients had emergency angiography on Day 0, within 5 hours of the latest rupture. The prognosis was very poor. We stressed the importance of the time interval between the latest rupture and angiography.
Subject(s)
Humans , Aneurysm , Angiography , Cerebral Angiography , Emergencies , Intracranial Aneurysm , Prognosis , RuptureABSTRACT
We report a rare case of scalp AVM concurrent feeding from external carotid artery and internal carotid artery, namely, superficial temporal artery and ophthalmic artery. This 20-year-old woman was seen because of serpiginous pulsatile mass in the frontal scalp, and the mass was enlarged during pregnancy. The case that feeding from the internal carotid artery branch is very rare. Angiography, MRI and MR angiography findings are presented.