1.
Chinese Pharmaceutical Journal
;
(24): 111-1999.
Article
in Chinese
| WPRIM
| ID: wpr-598314
ABSTRACT
OBJECTIVE:To eualuate in vitro antibacterial activities of silver nitrate and povidone-iodine for preventing ophthalmia neonatorum. METHODS:Minimal inhibitory concentration(MIC) and mininmal bactericidal concentration (MBC) were deter-mined by double broth dilution method. RESULTS:For Stapanrens Streppnenmonia and N gonorhveae,the MIC50 of silver nitrate were<4~8μg.ml-1 and its MIC90 were 8~32μg.ml-1.The MIC50 of povidone-iodine were64~256μg.ml-1 and its MBC90were 512 μg.ml-1. CONCLUSION: Silver nitrate and povidone-iodine exhibited activities against common pathogens of ophthalmia neonatorum isolates.Silver nitrate was more active than povidone-iodine.