Seroprevalence and risk factors for hepatitis C virus infection in pregnancy

This study aims to determine the prevalence of anti-HCV antibodies among pregnant women admitted to Antenatal Care Unit, Mansoura University Hospital, Egypt and to identify the risk factors for the disease among those women and their husbands. Screening of pregnant women for anti-HCV antibodies by ELISA second generation, HBsAg and anti-HIV antibodies Risk factors for HCV infection among those women and their husbands were recorded. This study indicates that the prevalence of anti-HCV antibodies among 767 pregnant women was 13.69%, HBsAg 2.35% and no cases of anti-HIV antibodies were encountered. The most important risk factors for HCV infection were surgical operations [60.95%], bilharziasis [27.62%] and blood transfusion [22.86%]. Husbands risk factors included travelling abroad [37.14%] and surgical operations [12.38%]. No risk factors were identified in 16.19% of women and 55.24% of their husbands. The prevalence of anti HCV antibodies [13,69%] is higher among pregnant women presenting to Mansoura university Hospital than those reported by other Studies. Schistosomiasis and husband travelling abroad were two important risk factors for HCV infection

Acceptability of the norplant subdermal implants

A total of 344 women was selected to evaluate the acceptability of norplant. Changes in the menstrual pattern were the most frequent side effects reported. However, such changes diminished with time and by the end of 12 months after insertion 7.1% of users experienced no change in cycle length and about 85% considered their menstrual pattern to be normal. Non-menstrual side effects were not persistent and not constituting a problem. The continuation rate was 86.337% and the pregnancy rate was 0.29/100 w.y., i.e. the continuation rate and the effectiveness are high

Hysteroscopically directed endometrial biopsy versus full endometrial curettage in perimenopausal bleeding

Hysteroscopically guided biopsy was evaluated versus full curettage biopsy in 50 patients presented with perimenopausal bleeding. The presenting symptom was metrorrhagia in 58%, menometrorrhagia in 24% and menorrhagia in 18% of cases. Two specimens of the hysteroscopic directed biopsies were unfit for histopathologic examination Endometrial hyperplasia was diagnosed in 66% of the hysteroscopic biopsies and 74% of the full curettage biopsies. The overall diagnostic efficacy of hysteroscopic biopsy in diagnosing endometrial pathology was 84% for simple endometrial hyperplasia 92% for cystic endome trial hyperplasia, 96% for regressive hyperplasia, and 88% for proliferative endometrium. There was an agreement between the two procedures in 76% of cases. Hysteroscopy revealed more informations in 24% of cases

comparative study between intra-uterine insemination [IUI-husband] and direct intraperitoneal insemination [DIPI-husband] in the treatment of male infertility

In this study, 109 infertile couples due to male factor were evaluated to compare the results of [IUI husband] and [DIPI- husband] in normal and stimulated cycles.The study revealed that IUI and DIPI are of minimal therapeutic effect in the treatment of male factor of infertility in normal cycles. However, when the cycle were stimulated the conception rate increased from 5.2% to 11.3% in IUI and increased from 3.6% to 10.3% in DIPI. There are in male infertility IUI and DIPI with stimulated cycles deserve trial before attempting the more invasive, costly and complicated assisted reproductive technology

Vaginal and cervical cytology in cervical eversion [cervical erosion] and suspicious cervix

This study was carried out on 200 non-pregnant women, with ages ranging from 18 up to 48 years. They attended the gynaecologic outpatient clinic, at Mansoura University Hospital. They include 150 women with cervical erorsion and suspicious cervix and 50 women with clinically healthy cervices as controls. A posterior vaginal pool and cervical scraps smears were obtained from each woman using the plastic spatula and stained by Papanicolaou stain. There was an increased incidence of dysplasia among parous women than nulliparous women. Also we found 3 cases of invasive carcinoma of the cervix among the suspicious cervix group and this was proved histopathologically. The chief complaint of cases with cervical erosion was excessive vaginal discharge [57%]. The incidence of dysplasia among cervical erosion groups was 34% [41 out of 120 cases], while the incidence in the suspicious cervix group 52% [14 out of 27 cases] no cases of dysplasia had been found in the control group. We can recommend that each woman during her reproductive period must be checked up by routine cervico-vaginal cytology every 6 months to detect and early lesion which could be easily dealt with as early as possible and abort it before it grows up