ABSTRACT
@#Abstract: Objective To analyze the clinical characteristics and changes of serum IgG, IgM antibodies in patients infected with the SARS-CoV-2 B.1.1.529 (Omicron) variant. Methods The clinical data of 82 patients with SARS-CoV-2 B.1.1.529 variant was analyzed retrospectively. Based on the presence of pneumonia on chest CT, the patients were divided into pneumonia group and non-pneumonia group. Serum IgG, IgM antibodies were observed at 5 time points T1 (1~<4 d), T2 (4~<8 d), T3 (8~<15 d), T4 (15~<22 d) and T5 (22~<30 d) after admission. Results Among the 82 patients infected with the SARS-CoV-2 B.1.1.529 variant strain, there were 62 cases of cough, 31 cases of fever, 33 cases of throat discomfort, 5 cases of muscle soreness and 3 cases of diarrhea. The serum IgG antibody levels at 5 time points were 50.22 (142.20) AU/mL, 326.50 (220.63) AU/mL, 368.23 (76.21) AU/mL, 368.65 (79) AU/mL, and 385.26 (113.10) AU/mL, respectively. The level of serum IgG antibody in the pneumonia group was lower than that of the non-pneumonia group at T1 and T4 time points, and the differences were statistically significant (P<0.05) , the positive rate of serum IgG antibody in the pneumonia group was lower than that of the non-pneumonia group at the T1 time point, and the difference was statistically significant (P<0.05) . The serum IgM antibody levels at 5 time points were 0.41 (0.81) AU/mL, 0.95 (1.62) AU/mL, 1.09 (2.42) AU/mL, 0.74 (3) AU/mL, and 0.81 (3.10) AU/mL respectively, and there was no significant difference between the two groups. Conclusion The clinical symptoms of patients infected with the SARS-CoV-2 B.1.1.529 variant strain are mild. Serum IgG antibodies increased after infection, but there are some differences between the pneumonia group and the non-pneumonia group, whether serum IgG has a protective effect needs further research; the serum IgM antibodies do not increase highly after infection, there are some differences between individuals.
ABSTRACT
The aim of our study was to observe the occurrence rate and morphological characteristics of Infra-Lamina ridge (ILR) in Chinese population and provide a comprehensive reference for its clinical implication. Vertebrae columns of 82 sets of Chinese adult skeletons were collected. The shape of ILR was classified into three types; the occurrence of it in different sides and sexes were counted. The length, width, thickness of ILR were measured using a caliper with 0.02 mm accuracy. The ILR was usually found to occur from C7 to L5, with its frequency higher from T8 to 12, and highest at T10being up to 80.5%. There was significant statistical difference to the occurrence rate by side, sex and vertebral level. The largest values in its length and width were from T9 to T12. The ILR at T10 was largest in dimensions, being 4.1±2.1 mm in length and 4.4±2.3 mm in width. The ILR is more frequently detected in female and at the left side, at the lower thoracic spine with a larger dimension.
El objetivo de nuestro estudio fue observar la tasa de incidencia y características morfológicas del puente infra-laminar (PIL) en la población china y ofrecer una referencia completa por su implicación clínica. Se utilizaron 82 series de vértebras pertenecientes a esqueletos adultos chinos. La forma del PIL se clasificó en tres tipos; además se cuantificó la presenciade la misma en diferentes lados y sexos. La longitud, ancho y grosor del PIL se midieron utilizando un caliper con 0,02 mm de precisión. Se encontró que el PIL por lo general se producía desde C7 a L5 , con una mayor frecuencia entre T8 y T12, la más alta en T10 donde alcanzó el 80,5%. No hubo diferencia estadísticamente significativa en la tasa de ocurrencia según lado, sexo y el nivel de la vértebra. Los mayores valores de longitud y ancho fueron de T9 a T12. El PIL en T10 tuvo las mayores dimensiones, con una longitud de 4,1±2,1 mm y ancho de 4,4±2,3 mm. El PIL se detecta con mayor frecuencia en mujeres y la lado izquierdo, con una mayor dimensión en la columna torácica inferior.