ABSTRACT
Objective@#To explore the influence of pubertal timing on learning adaptation in junior high school students, so as to provide reference for the prevention and intervention of junior high school students learning adaptation.@*Methods@#From April to June 2019, 1 677 students were sampled by stratified cluster sampling from three middle schools in Zhoukou and Xiangcheng, Henan Province. The Chinese version of Youth Development Scale and Learning Adaptation Scale were used for questionnaire survey.@*Results@#The scores of learning task, learning attitude and learning achievement of female students were higher than those of male students, and the differences were statistically significant(t=-2.34, -2.14, -5.81, P<0.05); The learning attitude, academic performance, interpersonal environment score of grade 7 were higher than that of grade 9, the total learning adaptation score of grade 7 was higher than that of grade 8, the differences were statistically significant(F=1.95, 1.87, 2.24, 1.37, P<0.05). Partial correlation analysis showed that junior high school students pubertal timing was negatively correlated with the total scores of learning tasks and learning adaptation(r=-0.15, -0.13, P<0.05). The scores of learning task, total score of learning adaptation and academic performance of the earlier group were lower than those of the later group, and the scores of learning attitude of the earlier group were lower than those of the moderate group, the differences were statistically significant(F=4.76, 1.97, 3.23, 3.80, P<0.01). Regression analysis showed that pubertal timing had a significant negative predictive effect on learning adaptation scores and learning tasks(β=-0.12, -0.13, P<0.05).@*Conclusion@#The pubertal timing of junior high school students is closely related to learning adaptation, and pubertal timing will lead to the increased risk of learning adaptation of junior high school students. Schools should carry out corresponding health education and provide professional psychological counseling services, so as to improve the learning adaptation among early starters.
ABSTRACT
The clinical value of transvaginal ultrasound in clinical surgical treatment of cesarean scar pregnancy (CSP) was evaluated.The clinical data of 104 patients with CSP admitted at Tongji Hospital from 2013 to 2016 were collected and analyzed retrospectively,including the patients' age,gestational age,the size of gestational sac or uneven mass,the uterine scar thickness,β human chorionic gonadotropin (hCG) levels and so on.Of these 104 cases,30 cases were subjected to laparotomy,29 cases to laparoscopy,27 cases to hysteroscopy,16 cases to ultrasound-guided uterine curettage,and 2 cases to conservative treatment.The transvaginal ultrasound showed that uterine scar thickness and gestational sac or uneven mass size had significant difference (P＜0.05) among different surgical methods by comparatively analyzing the patients' data.It was suggested that transvaginal ultrasound may provide the valuable reference for choosing clinical surgical procedures for CSP.
ABSTRACT
During placental development,oxygen environment is not only critical for trophoblasts migration and invasion,but also fundamental for appropriate placental perfusion.Cysteine-rich 61 (Cyr61,CCN1) was expressed in the extravillous trophoblasts (EVTs) and decreased in preeclampsia.Its regulatory properties in human first-trimester extravillous trophoblast cell line (TEV-1 cells) upon a low oxygen tension were investigated.The present study examined functional changes involved in adaptation to hypoxia of the TEV-1 cells,using cobalt chloride (CoCl2) as hypoxic mimic.It was found that hypoxia inhibited growth of TEV-1 cells and induced the increase of cell apoptosis (P＜0.05).The Cyr61 expression in human EVTs was transcriptionally induced by CoCl2.Inappropriate EVTs apoptosis has been implicated in the failure of trophoblasts to fully invade and modify the uterine environment and Cyr61 down-regulation,potentially leading to preeclampsia.