ABSTRACT
An association between HTLV-1 infection and infective dermatitis(ID), a relapsing eczematous condition of Jamaican children, was reported in 1990. These patients are at a risk of developing other known HTLV-1 related diseases. We have observed the development of HTLV-1 associated myelopathy/tropical spastic paraparesis im two patients, ages 14 and 35 years, who were diagnosed with ID at ages 2 and 10 years, respectively. Infective dermatitis of children serves as an early marker of HTLV-1 infection and may predict later development of either the malignant outcome, adult T-cell leukaemia/lymphoma or the neurologic manifestation HAM/TSP among adult carriers of HTLV-1 infection
Subject(s)
Humans , Female , Child , Staphylococcal Infections/complications , Streptococcal Infections/complications , HTLV-I Infections/complications , Paraparesis, Tropical Spastic/etiology , Dermatitis/complications , Follow-Up Studies , Jamaica/epidemiologyABSTRACT
A review of dermatofibrosarcoma protuberans diagnosed at the University hospital of the West Indies over a 10-year period revealed 23 cases. The mean age of the patients was 36.3 years. There were 13 females and 10 males. The trunk was the most common site. The clinical diagnosis was commonly missed. The results of this study are compared with those from other countries
Subject(s)
Adult , Middle Aged , Humans , Male , Female , Skin Neoplasms/pathology , Dermatofibrosarcoma/pathology , Skin Neoplasms/diagnosis , Skin Neoplasms/therapy , Retrospective Studies , Dermatofibrosarcoma/diagnosis , Dermatofibrosarcoma/therapyABSTRACT
A randomized controlled trial of Solcoseryl, DuoDerm and conventional conservative therapy with Eusol has been performed in 32 patients with homozygous sickle-cell (SS) disease. After 12 weeks' baseline observation, patients were randomized to one of three therapies and monitored for a further 12 weeks. Of 44 ulcerated legs, 20 received control treatment, 12 Solcoseryl and 12 DuoDerm. DuoDerm was generally unacceptable, and two-thirds of the patients defaulted from this treatment. Solcoseryl increased ulcer healing compared to the controls but the difference was not significant. Solcoseryl was well tolerated and may have a role in the treatment of chronic leg ulcers of sickle-cell disease.
Subject(s)
Humans , Male , Female , Actihaemyl/therapeutic use , Colloids/therapeutic use , Anemia, Sickle Cell/complications , Leg Ulcer/drug therapy , Occlusive Dressings , Randomized Controlled Trials as Topic , Patient Compliance , JamaicaABSTRACT
We herein report the case of a black pregnant teenager with Type 1 Ehlers-Danlos syndrome. A successful abdominal delivery was achieved at 38 weeks' gestation.