ABSTRACT
Objective:To explore therapeutic effect of noninvasive ventilator on advanced aged patients with acute de- compensated chronic heart failure.Methods:A total of 196 advanced aged patients with acute decompensated chron- ic heart failure hospitalized in our department were randomly and equally divided into routine treatment group and noninvasive ventilator group (received auxiliary treatment with noninvasive ventilator based on routine treatment group).Total effective rate,respiratory rate (RR),heart rate (HR),mean arterial pressure (MAP),partial pres- sure of oxygen in artery (PaO2 )and left ventricular ejection fraction (LVEF)were observed and compared between two groups before and after treatment. Results:Compared with routine treatment group, total effective rate (73.47% vs.90.82%)significantly rose in noninvasive ventilator group,P=0.007. There were no significant difference in above each indexes between two groups before treatment (P>0.05).Compared with before treat- ment,there were significant reductions in RR,HR and MAP,and significant rise in PaO2 and LVEF in both groups after treatment,P<0.05 or<0.01;compared with routine treatment group after treatment,there were significant reductions in RR [(27±6)times/min vs.(19±3)times/min],HR [(109±10)beats/min vs.(73±8)beats/min] and MAP [(110.5±9.0)mmHg vs.(81.6±8.0)mmHg],and significant rise in PaO2 [(77±8)mmHg vs.(98 ±9)mmHg]and LVEF [(41.9±5.4)% vs.(52.7±5.5)%]in noninvasive ventilator group,P<0.05 or<0.01. Conclusion:Noninvasive ventilator treatment based on routine therapy can effectively relieve symptoms of heart fail-ure,improve RR,HR,MAP,PaO2 ,LVEF and cardiac function in advanced aged patients with acute decompensat- ed chronic heart failure,which is worth extending.