ABSTRACT
There were eleven cases of pure red cell aplasia diagnosed over a period of 2 years (January 2000-December 2001). All the patients had anemia with pallor and weakness being the presenting complaints. Hematological profile depicted normocytic normochromic anemia, reticulocytopenia and marked paucity of erythroid precursors on bone marrow aspiration and biopsy studies. In the present study, one case was of congenital pure red cell aplasia, in one other case of pyrexia of unknown origin, no definitive diagnosis could be made. Other associated diseases seen with pure red cell aplasia were thymoma, septicemia, protein energy malnutrition, non-Hodgkin's lymphoma, juvenile rheumatoid arthritis, acute myeloid leukemia, tuberculosis and hepatitis C. The association of pure red cell aplasia with haematologic malignancies is rare. There are very few case reports on pure red cell aplasia with hepatitis C.
Subject(s)
Adolescent , Adult , Bone Marrow/pathology , Child , Child, Preschool , Female , Hepatitis C/complications , Humans , Infant, Newborn , Lymphoma, Non-Hodgkin/complications , Male , Middle Aged , Nepal , Red-Cell Aplasia, Pure/complications , Thymoma/complications , Thymus Neoplasms/pathologyABSTRACT
A case with massive ovarian edema (MOE) of left ovary--a rare pseudotumour and mature cystic teratoma of right ovary is described in a young unmarried girl of 16 years. The etiopathological concepts, morphological changes and differential diagnosis are described. Knowledge about the entity and its existence are important for correct treatment. This is the first reported case from Nepal.
Subject(s)
Adolescent , Edema/complications , Female , Humans , Nepal , Ovarian Diseases/complications , Ovarian Neoplasms/complications , Teratoma/complicationsABSTRACT
Microcystic papillary adenoma of nose is rarely seen in nose. This case is reported because of its rarity and to best our knowledge is a first case report from Nepal.
Subject(s)
Adenoma/pathology , Female , Humans , Middle Aged , Nose Neoplasms/pathologyABSTRACT
An unusual case of massive cystic degeneration in an uterine leiomyoma measuring 21 cm in diameter, in a 40 year old female is being presented. It was diagnosed as a cystic adnexal tumor on ultrasonogram. Interlacing bundles of smooth muscle were identified in the cyst wall, which was confirmed on special stains. The differential diagnoses considered in this case are discussed. To the best of our knowledge, this is the largest cystic degeneration in an uterine leiomyoma reported in the literature.
Subject(s)
Adult , Diagnosis, Differential , Female , Humans , Leiomyoma/pathology , Ovarian Cysts/pathology , Uterine Neoplasms/pathologyABSTRACT
Endometriosis is described as the presence of endometrial glands or stroma in abnormal locations outside the uterus. It afflicts 10% women of childbearing age. A 5-year retrospective analysis of histopathologically proven cases of endometriosis was done. Haematoxylin and Eosin stained slides were reviewed for type of lining epithelium, endometrial glands, stroma, fresh and old hemorrhage & inflammatory cells. Clinical details were analyzed. Age of the patient ranged from 22 - 48 years. The most common site of endometriosis was ovaries (69.23%) followed by scars (11.43%), cervix (7.69%), fallopian tube (3.84%), vagina (3.84%) and appendix (3.84%) in descending order of frequency. Most common symptom was pain. On ultrasound and X-ray diagnosis could not be made in any case. Clinically endometriosis was diagnosed in 9 (34.62%) cases. On histopathological examination majority of the cases (42.3%) had endometrial glands, stroma and hemosiderin laden macrophages. 3 cases (11.43%) had endometrial lining epithelium and stroma only, which on laproscopy also were diagnosed to have endometriosis. It was concluded that high rate of surgical excision of organs were done because of misdiagnosis.
Subject(s)
Adult , Endometriosis/diagnosis , Female , Humans , Incidence , Middle Aged , Nepal/epidemiology , Retrospective StudiesABSTRACT
A 15-year-old girl with Duke's B mucinous carcinoma of the rectosigmoid was treated with surgical resection and adjuvant chemotherapy. The patient is alive and has been disease-free for 15 months. Colorectal carcinoma is extremely rare in children and adolescents. Adenocarcinoma of colon is a virulent disease in children and has a poor prognosis. This is because of the poor histological characteristics and difficulty in diagnosis.