ABSTRACT
Mucormycosis or black fungus previously called as zygomycosis is not a common fungal disease. It occurs in the patients with low neutrophil counts, severe malnutrition and hematological malignancies. Mucor mycosis also common in patients with tuberculosis, diabetes mellitus, COVID-19 and steroid therapy since all these conditions lead to low immunity. Mucormycosis involves different body organs like nose, orbit, brain, skin, gastrointestinal tract, lung, blood and is classied accordingly. Infection mainly enters in the body through nose and mouth or through cuts present over the skin. In case of rhino-orbito-cerebral type of mucormycosis the clinical feature might be from nasal blockage and crusting to life threatening complication like brain abscess and meningitis. The treatment for mucor mycosis might be antifungal drugs alone or combined with surgical debridement depending upon involvement of vital structure and complications. After covid-19 infection, incidence of rhino-orbito-cerebral mucor mycosis increased. The rare disease is to be common due to multiple factors in covid-19 infected patients. Diabetes was a major etiological factor because high blood glucose level and acidosis is responsible for virulence and survival of the fungi. Most common clinical feature was nasal blockage and crusting of nasal cavity mucosa and most common involved sinus was maxillary sinus while involvement of maxillary sinus with ethmoid sinus was highest.