ABSTRACT
The diagram of immune system with antigene was the toxic extract from the repeating stage, making the rough serum up to the lowest of 150 Lf/ml (or 210IU/ml) and applied the method of taking horse’s blood and giving back red blood cells to increase the the rough serum two times. The new process did reduce the level fN-protein, time and increase the quantity and productivity of the purified serum. The purified serum was of high quality: clear color, low level of N-protein to 30% compared with registered standard (150mg/ml).
Subject(s)
Tetanus Antitoxin , SerumABSTRACT
Rabies is a common contagious disease of human and animals (dog, cat, monkey...) that caused by a virus. In Vietnam, normally every year has from 300 to 500 people die of rabies (equally one fourth of total deaths caused by contaminated diseases, 95% of deaths without vaccination in time. When was bitten by mad dog or having large, deep and dangerous wound that near the nervous centre, the surface of genitourinary... there must be used right away antiserum besides vaccine. Subjects are more likely infected with mad virus who need to vaccinate before
Subject(s)
Humans , Animals , Rabies , Vaccination , VirusesABSTRACT
Selection of bacteria classification, collection the normal groups in sterility of vaccine and substances of national Institute of Vaccines (IVAC) of Nha Trang - Da Lat during 20 years (from 1983 to 2003). Cultured environment thioglycolate and Sabouraud. Gram's stain method and recognized and biochemical test were applied routinely by WHO. A computer software based on bacteria classification and SQL language in MS Access were developed by IVAC. This program was used for controlling sterility of vaccine and substances to follow GMP requirement in the future
Subject(s)
Infertility , Vaccines , Software , ClassificationABSTRACT
In the last 11 years recently the contaminated rate was very low (291/6382 samples). 0.45% and decreased dramatically in the past 3 years (2000-2003 period). The most common contaminated germs were primarily gram(+) bacteria (60% - 195/320 samples). 4.6% of samples were contamined with fungi (15/320), which should be erradicated completely
Subject(s)
Biochemistry , Bacillus subtilis , ProbioticsABSTRACT
The Institute of Vaccine and Biologicals has recently released on market a purified tetanus antitoxin. The average potency of the product reached 3.000 IU/ml. The N-protein content is 70mg/ml
Subject(s)
Tetanus Antitoxin , Disease , TetanusABSTRACT
The Institute of Vaccine had elaborated a procedure of preapration and produced successfully a 4 component liquid vaccine of diphteria – tetanos – coqueluche and meningitis (DTP-Hib). The quality have reached the standards issued in European and WHO Pharmacopoeia. The procedure of preparation of DPT-Hib mixt vaccine and the preliminary procedure of its quality control were established