Effect of metformin and flutamide on anthropometric indices and laboratory tests in obese/overweight PCOS women under hypocaloric diet

This study was designed to investigate the effect of metformin and flutamide alone or in combination with anthropometric indices and laboratory tests of obese/overweight PCOS women under hypocaloric diet. This single blind clinical trial was performed on 120 PCOS women. At the beginning, hypocaloric diet was recommended for the patients. After one month while they were on the diet, the patients were randomly divided in 4 groups; metformin [500 mg, 3/day], flutamide [250 mg, 2/day], combined, metformin [500 mg, 3/day] with flutamide [250 mg, 2/day] and finally placebo group. The patients were treated for 6 months. Anthropometric indices and laboratory tests [fasting and glucose-stimulated insulin levels, lipid profile and androgens] were measured. A one-way ANOVA [Post Hoc] and paired t-test were performed to analyze data. A p

Assessment of the prevalence of kyphosis disorders in students

The aim of this study was to assess the prevalence of kyphosis disorders in students. Five hundred and two students in three levels including primary [99 girls, 99 boys] guidance]47 girls, 57 boys], and high schools [100 girls, 100 boys] participated in this study. Frontal Cobb angle was measured by flexi curve ruler. Data were analyzed by chi square. After collecting the data, subjects were classified in 4 categories includeing flat back, normal, kyphosis, and hyperkyphosis. In all 256 boys, 2% had flat back [2%], normal [76.6%], kyphosis [21.4%] and in 256 girls [4.5%], showed flat Bach, flat back normal [80%], kyphosis [15%], but there were significant differences between their disorders [P > 0.05]. There was significant difference between boy and girls in elementary school [P < 0.05]. In guidance and high school boy and girls, there were significant differences between their spinal deformities [flat back, normal and kyphosis]. We concluded that reducing improper habits and familiarized the children with proper way of carrying her or his bags and performing proper activities such as sitting, sleeping and also participated in regular training, can reduces the risk of spinal deformities