ABSTRACT
Background: Type 1 diabetes mellitus is the most common endocrine disease in pediatric. We aimed to determine the demographic characteristics at presentation of childhood type 1 diabetes mellitus in Hamadan, west province of Iran
Methods: In this cross sectional descriptive study, demographic data of children with type 1 diabetes mellitus being followed up in Pediatric Endocrinology Clinic of Besat Hospital Hamedan Iran, were analyzed. A detailed record of the required information including the age, sex, Place of living[urban, rural], season, disease presentation, parental consanguinity [1st cousin relation],The mean mother's age at delivery, BMI ,birth seasonality and birth order were collected. The data was analyzed by standard statistical package SPSS, version 15.0. Results with p-value less than 0.05 were defined as statistically significant
Results: In total, 150 patients were included. The mean age at diagnosis was 8.47 +/- 3.17 yr. The majority of patients were urban. The frequency of disease was higher in summer. BMI percentile of most cases was between 5[th] to 85[th]. The frequency of positive family history was 10.7%. Among the studied patients, 18.7% had parental consanguinity. The mean mother's age at delivery was 25 +/- 5.3 yr. Of the studied patients, 82.7% were exclusively breastfeed and 43% were the first child of family. About 13.3% had co-occurring endocrine disease
Conclusions: Age at diagnosis and sex of our patients was similar to the world reported. But, seasonal variation is different in our region. The frequency of a family history of type 1 diabetes in first and second degree relatives was relatively high. Hypothyroidism was the most frequently observed co-occurring endocrine disease