Pulmonary leiomyoma in an HIV-infected child: A case report.

Smooth muscle tumors, benign or malignant, are rare in childhood. However, a higher incidence is found in HIV infected children with a reported association with Epstein-Barr Virus. We report a case of a 6-year-old HIV-infected girl who presented with a right upper lung mass and pulmonary tuberculosis. Histopathology of the resected mass showed a bronchiolar leiomyoma with adjacent noncaseous granulomas. Staining for AFB was negative. Polymerase chain reaction amplification for Mycobacterium tuberculosis complex was weakly positive. PCR amplification for EBV yielded a negative result.

Gastric perforation in very low birth weight infants following indomethacin administration: 2 case reports.

Two very low birth weight infant who had received intravenous Indomethacin for closure of ductus arteriousus developed massive pneumoperitoneum on the first and fifteenth day after administration. Isolated gastric perforation, sparing the entire intestine was found on laparotomy. Pathological findings in the first case shows transmural hemorrhage without inflammation. This report aims to discuss the contribution that Indomethacin makes in the pathogenesis of intestinal perforation in newborn patients.