ABSTRACT
We report an open trial study to determine the role of Helicobacter pylori (HP) in patients with non-ulcer dyspepsia (NUD) and to determine the effect of two drugs (colloidal bismuth subcitrate, CBS and cimetidine) on HP. Our study consisted of 48 patients, 30 received CBS two tablets twice daily and 18 received cimetidine 400 mg twice daily. The result of HP suppression detected by rapid urease test was 66.7% and 86.7% for CBS group after receiving the drug for 4 and 8 weeks respectively, for cimetidine only 11.1% urease test negative during the same period. Follow up urease test 19.2% of patients treated by CBS remained negative but none in the cimetidine group. AII patients felt better during treatment irrespective to status of HP. Our conclusion is that there is no correlation between HP status and NUD symptoms. To evaluate this relationship, further study must be done. To date there is no strong evidence to recommend HP eradication in HP associated NUP patients.
ABSTRACT
116 sera from cirrhotic patients were tested for HbsAg, Anti-HCV and Anti-HIV to assess the prevalence and determine risk factors of virus acquisition. Forty-two patients (36.21%) were positive for HbsAg, thirty patients (25.86%) were positive for Anti-HCV, five patients positive both HbsAg and Anti-HCV and only one patient (0.86%) was positive for Anti-HCV. There is no statistically different between risk factors (IVDU, prostitute, units of blood transfusion) and positity of viral markers, but alcohol seems to be less in HbsAg positive patients (p < 0.0001). For HIV the prevalrnce is comparable to general populations there is no need for routine Anti-HIV examination in cirrhotic patients with bleeding esophageal varices, but universal precaution is still the rule.