ABSTRACT
Objective:To explore changes of electrocardiogram (ECG)and cardiac markers,and its relationship with prognosis in aged patients with acute cerebral infarction.Methods:The data of 356 aged patients with acute cerebral infarction (acute cerebral infarction group),who hospitalized in our hospital from May 2007 to May 2012,and 258 non-cerebral infarction patients (normal control group)were retrospectively analyzed.Changes of ECG and cardiac markers were compared between two groups,and patients with cerebral infarction received a six-month follow-up. Results:Compared with normal control group,there were significant rise in percentage of abnormal ECG (22.9%vs.73.3%,χ2=150.53,P=0.00),levels of cardiac troponin I [cTnI,(0.02±0.003)μg/L vs.(0.07±0.002)μg/L],creatinine kinase isoenzyme [(9.1±5.6)U/L vs.(24.2±4.1)U/L]and creatinine kinase [(98±9.8)U/L vs.(202.7±10.2)U/L]in acute cerebral infarction group,P75 years:37.0% vs.83.8%,χ2=80.54,P=0.00);After six-month follow up,compared with normal group,there was significant increase in mortality rate (19.5% vs.86.8%,χ2=95.09,P=0.00)in acute cerebral infarction group.Conclusion:Incidence rate of abnormal ECG and cardiac marker level are higher in aged patients with acute cerebral infarction.It possesses important significance for judging patient′s condition,guiding treatment and evaluating prognosis.