ABSTRACT
Objective Human papilloma virus (HPV) infection can cause cervical cancer and other malignancies,so it is of vital importance to control HPV infection.The article was to investigate HPV prevalence and genotype distribution among females and their male partners in order to provide a basis for HPV prevention and control measures.Methods From Dermatology Departments of the First People's Hospital of Lianyungang City and Lianyungang Oriental Hospital during December 2015 and May 2016,we collected 110 females identified with HPV-positive by HPV detection of cervical epithelial cells and their typing results.Cervical exfoliative cells of female patients and urethral epithelial cells of their male sexual partners were collected for HPV typing test and genotype analysis.Results Among the cases,there were 68 cases of single gene type infection(61.82％),42 cases of multiple infections occurred (38.18％).As to their male partners,37 cases were detected HPV positive (33.64％),among which 23 cases were single gene type infection(62.16％),and 14 cases were multiple infection(37.84％).There were 21 HPV types in the detection of 110 HPV-infected females.There was significant statistical difference in the frequency of high-risk and low-risk HPV gene types between males and females(21 times vs 41 times,P＜0.05).The HPV anastomosis rate between sexual partners was 54.05％ (20/37),and the complete and partial coincidence rate was 27.03％ (10/37).Conclusion The male partners of HPV-infected females has high rate of HPV infection and they both have high type consistency.Therefore,it is necessary to control HPV infection in males and regular male HPV detection is very important.
ABSTRACT
<p><b>OBJECTIVE</b>We aim to explore the potential association between serum gamma-glutamyl transferase levels and functional outcome after aneurysmal subarachnoid hemorrhage in a Chinese population.</p><p><b>METHODS</b>A total of 386 aneurysmal subarachnoid hemorrhage patients were included in the study from September 2007 to February 2015. Baseline serum gamma-glutamyl transferase levels and 6-month follow-up functional outcomes were determined. A poor outcome was defined as a modified ranking scale score of ⋝ 3. The multivariable logistic model was used to analyze the relationship between serum gamma-glutamyl transferase and clinical outcomes after aneurysmal subarachnoid hemorrhage.</p><p><b>RESULTS</b>The adjusted poor outcome rates of patients with gamma-glutamyl transferase levels of < 30 U/L, 30-50 U/L and ⋝ 50 U/L were 16.7%, 19.6%, and 34.4%, respectively (P < 0.01). The age-sex and multivariable adjusted odds ratios (95% confidence intervals) of poor prognosis comparing the top group (⋝ 50 U/L) with the lowest group (< 30 U/L) were 5.76 (2.74-12.13), 6.64 (2.05-21.52), and 6.36 (1.92-21.02). A significant linear trend existed between gamma-glutamyl transferase level and aneurysmal subarachnoid hemorrhage prognosis. This association was also observed among nondrinkers.</p><p><b>CONCLUSION</b>Patients with higher gamma-glutamyl transferase levels were more likely to have a poor prognosis. Serum gamma-glutamyl transferase can be considered to be an independent predictor of functional outcomes after aneurysmal subarachnoid hemorrhage.</p>