ABSTRACT
Objective To evaluate the impact of Emotional Freedom Techniques on anxiety,depression and selfefficacy of elderly patients with type 2 diabetes mellitus.Methods Totally 120 elderly patients with type 2 diabetes mellitus complicated with anxiety and depression were randomly divided into the experimental group(n=60) and the control group(n=60).All patients received routine drug therapy and diabetic education,and patients in the experimental group performed Emotional Freedom Techniques for 4 weeks,10～15 min per time,3 times per day.Two groups were evaluated by Self-Rating Anxiety Scale,Self-Rating Depression Scale and Diabetes Self-Efficacy Scale before and after the intervention.Results The total scores of SAS and SDS in the experimental group after intervention were significantly lower than those before intervention and in the control group(P＜0.01).The total scores of DSES in the experimental group were significantly higher than those before intervention and in the control group (P＜0.01).Conclusion Emotional Freedom Techniques can effectively reduce anxiety,depression and improve self-efficacy of elderly patients with type 2 diabetes mellitus.
ABSTRACT
<p><b>BACKGROUND</b>High-dose chemotherapy followed by autologous stem cell transplantation (ASCT) is a promising approach for lymphomas. This study aimed to evaluate the effect of ifosfamide, cisplatin or carboplatin, and etoposide (ICE)-based regimen as a mobilization regimen on relapsed, refractory, or high-risk aggressive lymphoma.</p><p><b>METHODS</b>From June 2001 to May 2013, patients with lymphomas who mobilized by ICE-based regimen for ASCT were analyzed in this retrospective study. The results of the autologous peripheral blood stem cells collection, toxicity, engraftment after ICE-based mobilization regimen were analyzed in this study. Furthermore, risk factors for overall survival (OS) and progression free survival (PFS) were evaluated by univariate analysis.</p><p><b>RESULTS</b>The stem cells were mobilized using ICE-based regimen plus rituximab or ICE-based regimen alone in 12 patients and 54 patients, respectively. The results of stem cell mobilization were excellent. Ninety-seven percentages of the patients had the stem cell collection of at least 2.0 × 10 6 CD34 + cells/kg and 68% had at least 5 × 10 6 CD34 + cells/kg. Fifty-eight percentage of the patients experienced Grade 4 neutropenia, 20% developed febrile neutropenia, and only 12% had Grade 4 thrombocytopenia. At a median follow-up of 63.8 months, the 5-year PFS and OS were 64.4% and 75.3%, respectively.</p><p><b>CONCLUSION</b>ICE is a powerful regimen for stem cell mobilization in patients with lymphomas.</p>